alpha-Arbutin Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 84380-01-8 |
| Product name | alpha-Arbutin |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for alpha-Arbutin
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk alpha-Arbutin Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of alpha-Arbutin
| Industry | Application | Process |
|---|---|---|
| Cosmetics | Skin-lightening agent; inhibits tyrosinase activity and reduces melanin production | Prepared via chemical synthesis or biocatalytic conversion from hydroquinone and glucose, then purified and incorporated into skincare formulations such as emulsions and serums |
| Pharmaceuticals | Adjunctive treatment for hyperpigmentation disorders (e.g., melasma, age spots) | Formulated as an active pharmaceutical ingredient into topical gels, ointments, or oral capsules for dermatological clinical use |
| Household Chemicals | Anti-aging skincare ingredient to improve uneven skin tone | Used synergistically with antioxidants (e.g., vitamin C) in formulations; microencapsulation or sustained-release technologies enhance stability and skin permeability |
Manufacturing Quality Control of alpha-Arbutin
| Test Item | Common Test Methods | Method Overview |
|---|---|---|
| Content Determination | High-Performance Liquid Chromatography (HPLC) | An HPLC method using a reversed-phase C18 column, with methanol-water or acetonitrile-water as the mobile phase. Detection is performed using a UV detector (typically at 220–280 nm), with external standard quantification of α-Arbutin content. This method offers high sensitivity and excellent separation. |
| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Evaluation of purity based on the main peak area percentage in the HPLC chromatogram. The number and size of impurity peaks must meet pharmacopoeia or enterprise standards. |
| Impurity Testing | High-Performance Liquid Chromatography (HPLC) | Detection of possible organic impurities such as synthetic intermediates and degradation products (e.g., hydroquinone). Gradient elution is typically used to improve separation efficiency. |
| Residual Solvents | Gas Chromatography (GC) | Detection of residual organic solvents (e.g., methanol, ethanol, acetone) from the manufacturing process using a capillary column and FID detector, in compliance with ICH guidelines. |
| Water Content | Karl Fischer Titration | An electrochemical method for accurately determining water content in samples, suitable for quality control of solid active pharmaceutical ingredients. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Detection of heavy metal residues such as lead, arsenic, mercury, and cadmium, ensuring compliance with safety limits for pharmaceutical or cosmetic raw materials. |
| Microbial Limits | Microbial Culture Method | Testing for total aerobic microbial count, total mold and yeast count, and specified microorganisms (e.g., Escherichia coli), in accordance with pharmacopoeia requirements to ensure sterility or compliance with specified limits. |
| Crystal Form Analysis | X-Ray Diffraction (XRD) | Analysis of the crystal structure of α-Arbutin to identify different polymorphic forms, ensuring product consistency. |
| Infrared Identification | Fourier Transform Infrared Spectroscopy (FTIR) | Comparison of the sample's infrared spectrum with that of a reference standard or known spectrum to confirm characteristic functional groups, used for qualitative identification. |
| Melting Point Determination | Melting Point Apparatus | Determination of the melting temperature of α-Arbutin, used as a physical constant for identification and preliminary purity assessment. |
Technical Specifications of alpha-Arbutin
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 195.0 to 199.0 °C |
| Optical Rotation | +172 to +188° (c=1, in water) |
| Total Impurities | <=1.5% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of alpha-Arbutin
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of alpha-Arbutin
Packaging of alpha-Arbutin
Industrial alpha-Arbutin Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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