[1-(TERT-BUTOXYCARBONYL)-1,2,3,6-TETRAHYDROPYRIDIN-4-YL]BORONIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 844501-00-4 |
| Product name | [1-(TERT-BUTOXYCARBONYL)-1,2,3,6-TETRAHYDROPYRIDIN-4-YL]BORONIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 844501-00-4
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 844501-00-4 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 844501-00-4
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for anticancer drugs (e.g., EGFR inhibitors) | Used in Suzuki-Miyaura coupling reactions |
| Pharmaceuticals | Synthesis of neuroactive pharmaceuticals | Applied in boronate esterification and coupling |
| Chemical Reagents | Building blocks for organic synthesis | Employed in cross-coupling reactions |
| Materials Science | Construction of functional molecules | Utilized in palladium-catalyzed coupling |
Manufacturing Quality Control of 844501-00-4
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~210–230 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-MS | Separation and identification of impurities (e.g., residual starting materials, de-Boc products, oxidation by-products) via retention time matching and/or mass spectral confirmation. |
| Residual Solvents | GC-FID or GC-MS | Headspace GC analysis to quantify volatile organic solvents (e.g., THF, EtOAc, MeOH, DCM) based on calibrated external/internal standards. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration quantifying water via iodine generation and stoichiometric reaction with sample moisture. |
| Residual Metals (e.g., Pd, Ni, Cu) | ICP-MS or ICP-OES | Digestion followed by elemental quantification using plasma-based emission or mass spectrometry for trace metal catalyst residues. |
| Chloride Ion | Ion Chromatography (IC) or Potentiometric Titration | Anion separation and quantification via conductivity detection (IC) or argentometric titration with AgNO₃ endpoint detection. |
| Appearance & Color | Visual Inspection / APHA Color Scale | Subjective assessment against water-white standard or quantitative color measurement using APHA (Hazen) scale in solution. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by observing solid-to-liquid phase change under controlled heating rate. |
| Residual Boc Protecting Group Integrity | ¹H NMR Spectroscopy | Qualitative/quantitative assessment of t-butoxycarbonyl signal integrity (e.g., tert-butyl singlet at ~1.4 ppm) and absence of free amine peaks. |
| Boron Content | ICP-OES or Curcumin Spectrophotometry | Quantification of total boron after acid digestion (ICP-OES) or complexometric colorimetric assay using curcumin under acidic conditions. |
| Optical Rotation | [α]D Measurement (Polarimetry) | Determination of specific rotation using sodium D-line light to assess chiral purity (if applicable; compound is achiral but may contain chiral impurities). |
Technical Specifications of 844501-00-4
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 145–149°C |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 844501-00-4
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 844501-00-4
Packaging of 844501-00-4
Industrial 844501-00-4 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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