China Factory Direct
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| CAS number | 845256-59-9 |
| Product name | benzyl 3-fluoro-4-oxopiperidine-1-carboxylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a synthetic intermediate in the preparation of piperidine-containing drug molecules, such as NK1 receptor antagonists, analgesics, or candidate psychiatric agents | Introduced into multistep API synthesis routes via nucleophilic substitution, reduction, and deprotection reactions to incorporate the fluorinated piperidine scaffold |
| Agrochemical R&D | Potentially used to synthesize biologically active fluorinated heterocyclic compounds for exploration of novel pesticide lead structures | Employed as a building block in heterocycle modification for structure–activity relationship (SAR) studies and high-throughput screening |
| Organic Synthesis | Used as a fluorinated building block for constructing complex fluorinated molecules | Serves as a precursor in palladium-catalyzed coupling, amination, or transesterification reactions to deliver the 3-fluoro-4-oxopiperidine core structure |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at characteristic wavelength. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities by gradient HPLC separation and UV response. |
| Residual Solvents | GC-FID | Measures volatile organic solvents using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration based on iodine-sulfur dioxide redox reaction. |
| Heavy Metals | ICP-MS | Quantifies trace metal contaminants (e.g., Pb, Cd, Ni) via inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and conductivity detection. |
| Residual Palladium | ICP-OES | Measures palladium residue from catalytic steps using inductively coupled plasma optical emission spectroscopy. |
| Optical Rotation | Polarimetry | Determines specific rotation using sodium D-line light to assess chiral purity and enantiomeric excess. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid, indicating crystallinity and purity. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of particulates or foreign matter under controlled lighting. |
| Residue on Ignition | Gravimetric Analysis | Determines inorganic ash content by high-temperature incineration followed by weight measurement. |
| pH of Solution | pH Meter | Measures hydrogen ion activity in aqueous suspension or solution using calibrated glass electrode. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (by GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.