1-(Benzo[b]thiophen-4-yl)piperazine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 846038-18-4 |
| Product name | 1-(Benzo[b]thiophen-4-yl)piperazine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-(Benzo[b]thiophen-4-yl)piperazine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-(Benzo[b]thiophen-4-yl)piperazine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-(Benzo[b]thiophen-4-yl)piperazine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Pharmaceutical Intermediates | Serves as a key building block in the synthesis of SERMs (Selective Estrogen Receptor Modulators) or SERDs (Selective Estrogen Receptor Degraders), enabling construction of the benzothiophene-piperazine pharmacophore. |
| Pharmaceutical Industry | Drug Candidate Development | Applied in molecular design and structural optimization of antidepressants, antipsychotics, and anticancer agents—particularly for breast cancer treatment. |
| Chemical Synthesis | Organic Synthesis Building Block | Used in Suzuki coupling, Buchwald–Hartwig amination, or nucleophilic substitution reactions to construct complex bioactive molecules containing the benzothiophene scaffold. |
Manufacturing Quality Control of 1-(Benzo[b]thiophen-4-yl)piperazine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; reported as area percent relative to total chromatogram. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine, sulfur dioxide, and pyridine in methanol to determine water content by coulometric or volumetric titration. |
| Heavy Metals | ICP-MS | Quantitative determination of elemental impurities (e.g., Pb, Cd, Hg, As) by inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride anions using suppressed conductivity detection with an anion-exchange column. |
| Sulfate Impurity | Ion Chromatography | Separation and quantification of sulfate anions using suppressed conductivity detection with an anion-exchange column. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after high-temperature ashing at 700-800 C and weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, observed visually under controlled heating rate. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity of sample against defined standards under controlled lighting conditions. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution, indicating chiral purity and identity. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution in suspension using Mie scattering theory and laser diffraction instrumentation. |
Technical Specifications of 1-(Benzo[b]thiophen-4-yl)piperazine
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Melting Point | 124–128°C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-(Benzo[b]thiophen-4-yl)piperazine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-(Benzo[b]thiophen-4-yl)piperazine
Safety Information of 1-(Benzo[b]thiophen-4-yl)piperazine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1-(Benzo[b]thiophen-4-yl)piperazine
Industrial 1-(Benzo[b]thiophen-4-yl)piperazine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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