China Factory Direct
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| CAS number | 84624-28-2 |
| Product name | N'-Fmoc-L-lysine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Biopharmaceuticals | Intermediate for peptide synthesis | Used in solid-phase peptide synthesis (SPPS) as a lysine derivative with side-chain protection, providing an Fmoc-protected ε-amino group to facilitate subsequent coupling reactions |
| Pharmaceutical R&D | Development of antitumor drugs and targeted formulations | Introduced as a functionalized amino acid building block in the construction of peptide-based therapeutics or antibody–drug conjugates (ADCs) |
| Chemical Synthesis | Functional group modification of peptide molecules | Enables incorporation of modifiable lysine residues into peptide chains via Fmoc deprotection and coupling reactions, supporting crosslinking, labeling, or conjugation |
| Biomaterials | Design of functional biomaterials (e.g., nanocarriers) | Applied in synthesizing peptide-modified materials with targeting functionality to enhance biocompatibility or target specificity |
| Molecular Probes | Synthesis of fluorescently labeled or peptide-based probes | Used as a starting material to construct peptide probes bearing reporter or recognition groups for applications in bioimaging and detection |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 265 nm, comparing peak area to a certified reference standard. |
| Chiral Purity | Chiral HPLC | Separation of L- and D-enantiomers on a chiral stationary phase, with UV detection to determine enantiomeric excess. |
| Residual Solvents | GC-FID | Detection and quantification of common solvents (e.g., DMF, DCM, methanol) using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration with iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion and plasma excitation. |
| Residual Fmoc Chloride | GC-MS | Identification and quantification of unreacted Fmoc-Cl impurity by gas chromatography coupled with mass spectrometry. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., diketopiperazine, deprotected lysine) using gradient HPLC. |
| Loss on Drying | Gravimetric Analysis | Mass loss measured after controlled heating under vacuum or nitrogen to determine volatile and moisture content. |
| pH (1% w/v aqueous solution) | Potentiometric Titration | Measurement of hydrogen ion activity in aqueous suspension using calibrated pH electrode. |
| Specific Optical Rotation | Polarimetry | Determination of chiral compound concentration and enantiomeric identity via rotation of plane-polarized light at 589 nm. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using Mie scattering theory to derive volume-based particle size distribution. |
| Microbial Contamination | Membrane Filtration | Quantitative recovery of viable aerobic microorganisms from solution via filtration, followed by incubation on nutrient agar. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 168-172°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Optical Rotation | +15.0° to +19.0° (c=1, in 1M HCl) |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.