1-(Cbz-amino)cyclopropanecarboxylic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 84677-06-5 |
| Product name | 1-(Cbz-amino)cyclopropanecarboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-(Cbz-amino)cyclopropanecarboxylic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-(Cbz-amino)cyclopropanecarboxylic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-(Cbz-amino)cyclopropanecarboxylic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | As a pharmaceutical intermediate for synthesizing non-natural amino acid derivatives containing cyclopropane structures | Chiral synthesis or racemate resolution process |
| Pharmaceutical Chemicals | As a structural building block for peptide-based or peptidomimetic drugs | Solid-phase or liquid-phase peptide synthesis (SPPS/LPPS) process |
| Pharmaceutical Chemicals | As an intermediate for synthesizing ciprofloxacin-class or antiviral drugs | Amidation or condensation process of cyclopropanecarboxylic acid derivatives |
| Scientific Research | As an amino acid-protected derivative for studying the effect of cyclopropyl groups on protein conformation | Stereoselective synthesis and biological activity testing process |
Manufacturing Quality Control of 1-(Cbz-amino)cyclopropanecarboxylic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 210-230 nm, comparing peak area to a certified reference standard. |
| Chiral Purity | Chiral HPLC | Enantiomeric excess determination using a chiral stationary phase and UV detection, resolving R- and S-enantiomers. |
| Residual Solvents | GC-FID | Identification and quantification of common organic solvents (e.g., ethyl acetate, methanol, toluene) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water based on stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Residual Catalyst (Pd) | ICP-OES | Quantification of palladium residues after microwave-assisted digestion, using inductively coupled plasma optical emission spectroscopy. |
| Acid Value | Acid-Base Titration | Neutralization of carboxylic acid groups with standardized NaOH solution using phenolphthalein or potentiometric endpoint detection. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of visible particulates or foreign matter against established reference standards. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, using calibrated capillary apparatus per USP <741>. |
| Particle Size Distribution | Laser Diffraction | Measurement of size distribution in dry powder form using light scattering principles and Mie theory-based calculation. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., de-Cbz, hydrolyzed, dimeric species) using gradient reverse-phase HPLC. |
| Loss on Drying | Gravimetric Analysis | Weight loss measurement after controlled heating under vacuum or nitrogen, indicating volatile content including residual solvents and moisture. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric identity. |
| Microbial Contamination | Membrane Filtration | Enumeration of aerobic microorganisms and absence of specified pathogens (e.g., E. coli, Salmonella) per Ph. Eur. 2.6.12. |
Technical Specifications of 1-(Cbz-amino)cyclopropanecarboxylic acid
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 142–146°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | [α]²⁰D = -15.0° to -19.0° (c=1, in methanol) |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-(Cbz-amino)cyclopropanecarboxylic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-(Cbz-amino)cyclopropanecarboxylic acid
Safety Information of 1-(Cbz-amino)cyclopropanecarboxylic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1-(Cbz-amino)cyclopropanecarboxylic acid
Industrial 1-(Cbz-amino)cyclopropanecarboxylic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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