Fmoc-L-Glutamic acid 1-tert-butyl ester Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 84793-07-7 |
| Product name | Fmoc-L-Glutamic acid 1-tert-butyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Fmoc-L-Glutamic acid 1-tert-butyl ester
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Fmoc-L-Glutamic acid 1-tert-butyl ester Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Fmoc-L-Glutamic acid 1-tert-butyl ester
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | As a protecting group in drug synthesis | Temporarily protects the amino group of amino acids during peptide synthesis by forming a stable amide bond; prevents unwanted side reactions at the amino group in subsequent steps. The protecting group is removed under appropriate acidic conditions. |
| Biotechnology | Key raw material for peptide or protein synthesis | Used in solid-phase peptide synthesis (SPPS) to anchor Fmoc-L-glutamic acid 1-tert-butyl ester to a solid support or couple it with other amino acid units via specific coupling reagents, enabling stepwise assembly of the target sequence. |
| Chemical Research | Base material for synthesizing novel compounds | Acts as a key intermediate in synthesizing complex organic molecules—particularly those containing glutamic acid structural motifs—enabling site-selective functionalization through controlled introduction and removal of protecting groups. |
Manufacturing Quality Control of Fmoc-L-Glutamic acid 1-tert-butyl ester
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 260-280 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of structurally related impurities using gradient HPLC-UV, with identification by retention time matching and threshold-based reporting. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual solvents (e.g., DMF, THF, ethyl acetate) based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generation in pyridine-free reagents to determine trace water content via stoichiometric reaction. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific optical rotation at 589 nm using a polarimeter to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-MS | Quantification of toxic elements (Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppb sensitivity. |
| Residual Palladium | ICP-OES | Determination of Pd catalyst residues post-coupling reactions using inductively coupled plasma optical emission spectroscopy after microwave digestion. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection with an anion-exchange column and sodium carbonate eluent. |
| Residual TFA | GC-FID | Headspace GC-FID analysis to detect and quantify trifluoroacetic acid residue from deprotection steps using calibrated aqueous standards. |
| Particle Size Distribution | Laser Diffraction | Dry or wet dispersion followed by laser light scattering to determine D10, D50, D90 values per ISO 13320. |
| Melting Point | Capillary Melting Point Apparatus | Determination of onset and range of solid-to-liquid transition using calibrated digital melting point apparatus per USP <741>. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and absence testing for specified pathogens using membrane filtration and agar culture per USP <61> and <62>. |
Technical Specifications of Fmoc-L-Glutamic acid 1-tert-butyl ester
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -18.0° to -17.0° (c=1, in DMF) |
| Melting Point | 148°C to 152°C |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Fmoc-L-Glutamic acid 1-tert-butyl ester
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Fmoc-L-Glutamic acid 1-tert-butyl ester
Safety Information of Fmoc-L-Glutamic acid 1-tert-butyl ester
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Fmoc-L-Glutamic acid 1-tert-butyl ester
Industrial Fmoc-L-Glutamic acid 1-tert-butyl ester Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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