China Factory Direct
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| CAS number | 848093-36-7 |
| Product name | 2-Amino-5-iodo-3-pyridinecarboxylic acid ethyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeElectronic GradeMaterial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in the synthesis of antitumor agents and kinase inhibitors (e.g., BRAF inhibitor analogs) | Serves as a key iodinated heterocyclic building block in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck), enabling construction of target molecule core structures via coupling, hydrolysis, and amidation steps |
| Agrochemical R&D | Acts as a precursor to active ingredients in novel insecticides or fungicides | Introduces specific substituents via nucleophilic substitution or cycloaddition reactions to optimize inhibition of pest neuronal transmission or fungal cell wall biosynthesis |
| Organic Light-Emitting Materials | Used to prepare phosphorescent complex emissive layer materials based on iodinated nicotinic acid derivatives | Coordinates with transition metals such as iridium or platinum to form cyclometalated complexes, followed by ligand exchange and purification for vacuum thermal evaporation in OLED device fabrication |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities by separation on a C18 column with gradient elution and UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., ethanol, ethyl acetate) using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration with iodine-based reagent, based on stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Quantifies trace metals (Pb, Cd, Hg, As) after acid digestion using inductively coupled plasma mass spectrometry for high sensitivity. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with suppressed conductivity detection. |
| Residual Catalyst (Pd) | ICP-OES | Measures palladium residue after microwave digestion via inductively coupled plasma optical emission spectroscopy. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles against established visual standards under controlled lighting. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light by chiral compound in solution, indicating enantiomeric purity and identity. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry or wet dispersed sample using Mie scattering theory to determine size distribution profile. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148°C - 152°C |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.