(S)-2-{Bis[3,5-bis(trifluoromethyl)phenyl]hydroxymethyl}pyrrolidine Bulk Supply for Industrial Use

China Factory Direct
CAS number 848821-76-1
Product name (S)-2-{Bis[3,5-bis(trifluoromethyl)phenyl]hydroxymethyl}pyrrolidine
Stock Stock readily available; annual supply capacity exceeding 1,000 tons.
Grade Material GradeSpecialty GradeIndustrial Grade
Packaging 25KG/bag
Sample Test Samples Available (Click to Request Samples)
COA View COA
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Supply Type Bulk / Contract manufacturing / OEM
Shipping FCL / LCL available
Payment Terms Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C).
Manufacturer Greenrock Chemical(China Factory)
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CAS No:848821-76-1
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Documents We Provide for 848821-76-1

COA TDS SDS NMR MOA Certificate of Origin Transport Report TSCA Declaration Production Flow Chart
Pre-sale: Only COA, SDS and NMR are available.
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 848821-76-1 Supplier from China

17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.

Industrial Applications of 848821-76-1

Industry Application Process
Pharmaceuticals Chiral catalyst for asymmetric allylation, alkylation, and related reactions Used as a ligand to form chiral metal complexes (e.g., with Ir or Pd) that catalyze C–C bond formation
Fine Chemicals Chiral synthetic intermediate Applied in the synthesis of high-optical-purity pharmaceutical molecules and functional materials
Materials Science Precursor to chiral functional materials Employed in the construction of chiral luminescent materials or chiral sensing elements

Manufacturing Quality Control of 848821-76-1

Detection Item Common Analytical Method Method Overview
Assay (Purity) HPLC-UV Quantifies main component using reverse-phase HPLC with UV detection at 210-230 nm based on peak area comparison against reference standard.
Related Substances HPLC-UV Detects and quantifies structurally similar impurities using gradient HPLC-UV; identification via retention time matching with reference standards or spiked samples.
Residual Solvents GC-FID Separates and quantifies volatile organic solvents (e.g., methanol, THF, toluene) by gas chromatography with flame ionization detection using internal standard calibration.
Water Content Karl Fischer Titration Determines trace water by coulometric or volumetric titration where iodine generated electrochemically reacts stoichiometrically with water in anhydrous medium.
Optical Rotation [alpha]D Measurement Measures specific rotation using a polarimeter at 20 °C with sodium D-line (589 nm) to confirm chiral integrity and enantiomeric identity.
Heavy Metals ICP-MS Quantifies trace metal impurities (e.g., Pb, Cd, Ni, Fe) after acid digestion by inductively coupled plasma mass spectrometry with isotopic detection.
Chloride Impurity Ion Chromatography Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction and filtration.
Residue on Ignition Gravimetric Analysis Measures non-volatile inorganic residue after high-temperature ashing (700-800 °C) and precise weighing of the cooled crucible.
Melting Point Capillary Melting Point Apparatus Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus under controlled heating rate.
Appearance Visual Inspection Assesses physical state, color, and clarity of sample against standard references under controlled white light and specified viewing conditions.
Bulk Density USP <616> Tap Density Method Measures mass per unit volume after standardized mechanical tapping of a known powder mass in a graduated cylinder.
Particle Size Distribution Laser Diffraction Determines size distribution of solid particles in suspension using Mie theory-based analysis of laser light scattering pattern.

Technical Specifications of 848821-76-1

Test Item Specification
Appearance White to off-white crystalline powder
Purity >=98.5%
Total Impurities <=1.5%
Single Impurity <=0.5%
Melting Point 142-146°C
Optical Rotation +28.5° to +31.5° (c=1, CHCl3)
Water Content (KF) <=0.5%
Heavy Metals <=20 ppm
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com

Download COA of 848821-76-1

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NMR Spectra of 848821-76-1

Packaging of 848821-76-1

We have a diverse range of chemicals in stock. Available in Bagged goods (25 kg.),Big bags (500 kg.), Big bags (1000 kg.).

Industrial 848821-76-1 Procurement FAQ

1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.

2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.

3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.

4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.

5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.

6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.

7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.

8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.

9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.

Industrial
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Factory
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ISO 9001
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Samples
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