1-((4-Fluorophenyl)carbamoyl)cyclopropanecarboxylic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 849217-48-7 |
| Product name | 1-((4-Fluorophenyl)carbamoyl)cyclopropanecarboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-((4-Fluorophenyl)carbamoyl)cyclopropanecarboxylic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-((4-Fluorophenyl)carbamoyl)cyclopropanecarboxylic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-((4-Fluorophenyl)carbamoyl)cyclopropanecarboxylic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key chiral intermediate for the antidiabetic drug sitagliptin | Prepared via chiral synthesis processes—including asymmetric hydrogenation or enzymatic reduction—to produce the active pharmaceutical ingredient (API) of sitagliptin |
Manufacturing Quality Control of 1-((4-Fluorophenyl)carbamoyl)cyclopropanecarboxylic acid
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, state, and presence of visible impurities under natural light or standard illumination. |
| Identification | Infrared Spectroscopy (IR) | Compare the sample with a reference spectrum to confirm the presence of functional groups in the molecular structure (such as carboxyl, amide, aromatic rings, etc.) through characteristic absorption peaks. |
| Nuclear Magnetic Resonance Spectroscopy (¹H-NMR or ¹³C-NMR) | Analyze the chemical shift, coupling constants, and integral areas of hydrogen or carbon atoms to confirm the compound structure and ensure it matches the target. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a UV detector (typically at 254 nm or according to the maximum absorption wavelength) for quantitative analysis of the main component using external or internal standard methods. |
| UV-Visible Spectrophotometry (UV-Vis) | Quantitative analysis is performed based on the absorption characteristics of the compound at specific wavelengths. A standard curve must be established, and it is suitable for samples with high purity. | |
| Related Substances (Impurity) Testing | High-Performance Liquid Chromatography (HPLC) | Detect impurity peaks before and after the main peak using gradient or isocratic elution, calculate the content of each impurity and total impurity level to assess purity. |
| Moisture | Karl Fischer Titration (Karl Fischer) | Divided into volumetric or coulometric methods, which accurately determine the moisture content (crystalline water or adsorbed water) in the sample, suitable for trace moisture detection. |
| Residual Solvents | Gas Chromatography (GC) | Detect residual organic solvents (such as methanol, ethanol, dichloromethane, ethyl acetate, etc.) used during production according to ICH guidelines. |
| Melting Point | Capillary Melting Point Method | Determine the temperature range from initial melting to complete melting using a melting point apparatus, used to assess purity and identification. |
| Solubility | Solubility Test | Test the solubility of the sample in different solvents (such as water, ethanol, methanol, DMSO, etc.) to evaluate its physicochemical properties. |
| Heavy Metals | Atomic Absorption Spectrometry (AAS) or ICP-MS | Determine the residue levels of heavy metals such as lead, cadmium, mercury, and arsenic to ensure compliance with pharmacopoeia or international safety limits. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Method | After high-temperature carbonization and treatment with sulfuric acid, the sample is ignited to constant weight to determine the total amount of non-volatile inorganic impurities. |
| Clarity and Solution Color | Visual Color Comparison | Prepare a solution of a certain concentration and compare it with a standard color solution to evaluate the clarity and color of the solution according to specifications. |
Technical Specifications of 1-((4-Fluorophenyl)carbamoyl)cyclopropanecarboxylic acid
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.5% (by LC-MS) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Identification (NMR) | Conforms to reference spectrum |
| Identification (IR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-((4-Fluorophenyl)carbamoyl)cyclopropanecarboxylic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-((4-Fluorophenyl)carbamoyl)cyclopropanecarboxylic acid
Safety Information of 1-((4-Fluorophenyl)carbamoyl)cyclopropanecarboxylic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1-((4-Fluorophenyl)carbamoyl)cyclopropanecarboxylic acid
Industrial 1-((4-Fluorophenyl)carbamoyl)cyclopropanecarboxylic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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