China Factory Direct
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| CAS number | 849937-96-8 |
| Product name | 5-Bromo-2,4-dichloropyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of biologically active pyridine-based compounds, including antitumor, antiviral, and anti-inflammatory agents | Introduced into target molecular structures via organic synthesis reactions such as nucleophilic substitution, Suzuki coupling, and Buchwald–Hartwig amination |
| Agrochemicals | Used as an agrochemical intermediate in the synthesis of novel insecticides or herbicides | After halogen exchange or metallation (e.g., lithiation or magnesiation), reacted with carbonyl or heterocyclic reagents to construct the active molecular scaffold |
| Materials Science | Used to prepare nitrogen-containing heterocyclic functional materials, such as OLED materials or ligands | Employing transition metal-catalyzed cross-coupling reactions (e.g., Negishi or Stille coupling) to build conjugated systems or coordination structures |
| Test Item | Common Test Method | Method Summary |
|---|---|---|
| Assay | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with methanol-water or acetonitrile-water as the mobile phase. Detection is performed using a UV detector (approximately 260–280 nm), and quantification of the active ingredient is achieved via external or internal standard methods. |
| Purity and Impurity Analysis | Gas Chromatography-Mass Spectrometry (GC-MS) | Suitable for qualitative and quantitative analysis of volatile impurities. The sample is dissolved appropriately and injected, with organic impurities identified by comparison against mass spectral libraries. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Employs a gradient elution program to separate the main peak from impurity peaks, detecting and calculating the levels of individual impurities to assess sample purity. Total impurities are typically required to be below 0.5%. |
| Residual Solvents | Gas Chromatography (GC) | Detects organic solvents potentially remaining from manufacturing processes (e.g., methanol, ethanol, acetone, dichloromethane) in accordance with ICH guidelines. Headspace sampling is used to enhance sensitivity. |
| Water Content | Karl Fischer Titration | Utilizes electrochemical titration to accurately determine water content in samples, suitable for trace moisture detection (ppm level). |
| Bromine Content Verification | Elemental Analysis (EA) or ICP-MS | An elemental analyzer measures the proportions of elements such as C, H, N, and Br to verify molecular composition; alternatively, Inductively Coupled Plasma Mass Spectrometry (ICP-MS) is used for precise determination of bromine content. |
| Crystal Form / Physical Appearance | X-Ray Diffraction (XRD) | Analyzes the crystal structure of solid samples to identify polymorphic forms and ensure consistency in physical properties between batches. |
| Melting Point | Melting Point Apparatus | Determines the melting range using the capillary method, serving as a preliminary identification tool and purity indicator (impurities often lower the melting point and broaden the melting range). |
| Appearance and Color | Visual Inspection | Sample is examined under specified lighting conditions to confirm it is a white to off-white crystalline powder, free from visible foreign matter. |
| Particle Size Distribution | Laser Particle Size Analysis | Used to evaluate the particle size distribution of solid particles, which affects solubility and formulation performance—particularly important in formulation development. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 72.0–76.0°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.