8-Chlorotheophylline Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 85-18-7 |
| Product name | 8-Chlorotheophylline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 8-Chlorotheophylline
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 8-Chlorotheophylline Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 8-Chlorotheophylline
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of diuretic drugs | Used as an intermediate in chemical reactions |
| Pesticides | Raw material for plant growth regulators | Modified or derivatized |
| Chemicals | Production of other nitrogen-containing heterocyclic compounds | Substitution or condensation reactions |
| Food additives | Intermediate for feed additives | Esterification or acylation to produce target compounds |
Manufacturing Quality Control of 8-Chlorotheophylline
| Detection Item | Common Detection Methods | Method Overview |
|---|---|---|
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Utilizes a reverse-phase C18 column, with methanol-water or acetonitrile-water (containing buffering salts such as potassium dihydrogen phosphate) as the mobile phase, detected by a UV detector (typically at wavelengths 270–280 nm), and quantified using external or internal standard methods. It offers high selectivity and accuracy and is recommended by pharmacopoeias. |
| Purity Check | High-Performance Liquid Chromatography (HPLC) | Separates impurities through gradient or isocratic elution, calculates the total impurity content by comparing the area of the main peak, typically controlling single impurity ≤ 0.5% and total impurities ≤ 1.0%, in compliance with ICH Q3B guidelines. |
| Solvent Residue Detection | Gas Chromatography (GC) | Uses DB-624 or HP-INNOWAX capillary columns, FID detector, headspace or direct injection, and detects organic solvent residues such as ethanol, acetone, and dichloromethane according to the Chinese Pharmacopoeia Residual Solvents Monograph (Monograph 0861). |
| Moisture Determination | Karl Fischer Titration (KF) | Uses volumetric or coulometric methods to determine moisture content, suitable for trace water detection, ensuring moisture is controlled within ≤ 0.5% to avoid affecting stability and formulation processes. |
| Melting Point Determination | Melting Point Instrument Method | Measures the melting point range using a digital melting point instrument (literature value ≈ 198–202°C), serving as a physical characteristic identification basis and assisting in determining crystallinity consistency and purity. |
| UV Absorption Characteristics | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Measures the maximum absorption wavelength (λmax ≈ 275 nm) in methanol or ethanol solution, used for preliminary identification and concentration estimation, often as an auxiliary validation method for HPLC. |
| Identification Test | Infrared Spectroscopy (IR) | Obtains infrared spectra using KBr pellet or ATR methods, compares characteristic absorption peaks (e.g., C=O stretching vibration at 1680 cm⁻¹, C-Cl stretching vibration at 750–800 cm⁻¹) with standard spectra to confirm chemical structure consistency. |
| Heavy Metal Detection | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Digests samples according to the Chinese Pharmacopoeia Heavy Metals Test (Monograph 0821), measures lead, cadmium, arsenic, mercury, etc., and controls them to ≤ 10 ppm to ensure safety. |
| Chloride Residue Detection | Ion Chromatography (IC) | Uses an anion exchange column with suppressed conductivity detection to measure free chloride ion content in the sample, ensuring no excess inorganic chloride impurities (such as from synthetic raw materials or process by-products). |
Technical Specifications of 8-Chlorotheophylline
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 234-238°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 8-Chlorotheophylline
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of 8-Chlorotheophylline
Industrial 8-Chlorotheophylline Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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