China Factory Direct
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| CAS number | 85-38-1 |
| Product name | 3-Nitrosalicylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial GradeReagent GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceuticals | Synthesis of pharmaceutical intermediates | Used in the synthesis of anti-inflammatory, antimicrobial, and antipyretic analgesic drugs |
| Dyes | Synthesis of dye intermediates | Applied as an intermediate in the synthesis of azo dyes and other functional dyes |
| Pesticides | Fungicide synthesis | Employed as an intermediate in the synthesis of certain fungicides or plant growth regulators |
| Materials Science | Synthesis of functional materials | Utilized as a modifying monomer in the synthesis of certain polymers or functional resins |
| Chemical Reagents | Analytical reagent | Used as a colorimetric reagent or reference standard in analytical testing |
| Flavor & Fragrance Industry | Synthesis of fragrance intermediates | Involved in the synthesis of certain aromatic compounds |
| Environmental Science | Pollutant detection | Applied in spectroscopic detection methods for specific pollutants in water or soil |
| Test Item | Common Testing Method | Method Summary |
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| Purity and Content Determination | High-Performance Liquid Chromatography (HPLC) | Using a reverse-phase C18 column, with methanol/water or acetonitrile/water (containing a small amount of acid such as phosphoric or formic acid) as the mobile phase. The ultraviolet detector (UV) detects at wavelengths of 254–280 nm. Quantification is performed using external standard or internal standard methods, effectively separating 3-nitrosalicylic acid and its impurities (e.g., 2-nitrosalicylic acid, salicylic acid, etc.). |
| Melting Point Determination | Capillary Melting Point Apparatus Method | According to the Chinese Pharmacopoeia or USP methods, sample is loaded into a capillary tube and heated at a slow rate (1–2°C/min). The melting process is observed; the typical melting point for 3-nitrosalicylic acid is 158–162°C, used to initially judge purity and crystalline consistency. |
| Ultraviolet-Visible Absorption Spectrum | UV-Visible Spectrophotometry (UV-Vis) | The maximum absorption wavelength (λmax ≈ 240–280 nm) is measured in ethanol or aqueous solution. Quantitative analysis is performed using Beer's Law, suitable for rapid content screening but easily affected by impurities, often used as an auxiliary method. |
| Moisture Determination | Karl Fischer Titration (KF) | Using coulometric or volumetric Karl Fischer reagent titration to accurately determine trace moisture content in the sample (usually ≤0.5%), ensuring stability and storage quality of the sample. |
| Heavy Metal Detection | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After wet digestion of the sample, AAS or ICP-MS is used to detect heavy metal residues such as lead, cadmium, mercury, and arsenic, meeting pharmacopoeia limits (e.g., Pb ≤ 10 ppm), ensuring safety. |
| Related Substances (Impurity Profile) | HPLC-UV or HPLC-MS | Gradient elution HPLC combined with UV or mass spectrometry detection is used to qualitatively and quantitatively analyze possible nitration byproducts (e.g., dinitrosalicylic acid), unreacted raw materials (salicylic acid), oxidation products, etc., controlling total impurities ≤1.0%. |
| Chloride, Sulfate, and Other Inorganic Ions | Colorimetric Method (Pharmacopoeial Method) | Referring to the general rules of the Chinese Pharmacopoeia, chloride (as Cl⁻) and sulfate (as SO₄²⁻) content are detected by comparing with standard solutions, ensuring that inorganic impurities meet limit requirements. |
| pH Value Determination | Glass Electrode Method | A 1% aqueous solution is prepared and measured using a calibrated pH meter. A 3-nitrosalicylic acid solution shows weak acidity (pH ≈ 2.5–4.0), used to evaluate solubility and formulation compatibility. |
| Crystal Form and Structural Confirmation | Infrared Spectroscopy (FT-IR) or X-ray Diffraction (XRD) | Characteristic functional group absorption peaks (e.g., carboxylic acid ~1680 cm⁻¹, nitro group ~1530 cm⁻¹) are used to confirm molecular structure, or XRD is used to analyze crystal structure, ensuring consistency with the reference standard crystal form and avoiding polymorphic effects on stability. |
| Test Item | Specification |
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| Appearance | White to light yellow crystalline powder |
| Purity | >=98.0% (HPLC) |
| Melting Point | 192–196 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.