China Factory Direct
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| CAS number | 85068-27-5 |
| Product name | 2,5-Difluorophenylacetic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antiviral drug intermediates | Used as fluorinated arylacetic acid compounds to construct core drug molecular structures, e.g., for HIV protease inhibitors |
| Pharmaceuticals | Synthesis of non-steroidal anti-inflammatory drug (NSAID) intermediates | Applied in aromatic nucleophilic substitution or coupling reactions to introduce pharmacophores for developing novel anti-inflammatory and analgesic agents |
| Agrochemicals | Intermediates for plant growth regulators and herbicides | Employed in synthesizing fluorinated agrochemical active ingredients to enhance lipophilicity and biomembrane permeability |
| Organic Synthesis | Raw material for fluorinated fine chemical synthesis | Utilized as a fluorinated building block in Suzuki coupling, esterification, reduction, and other reactions to produce high-value fluorinated products |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 220 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and relative response factors. |
| Residual Solvents | GC-FID | Detection and quantification of volatile organic solvents (e.g., methanol, ethyl acetate) using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry for ultra-trace sensitivity. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 700-800 C followed by weighing of non-volatile inorganic residue after sulfuric acid treatment. |
| Optical Rotation | [alpha]D Measurement | Determination of specific optical rotation using a polarimeter at 20 C with sodium D-line (589 nm) to confirm chiral integrity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed as solid-to-liquid phase change using calibrated capillary apparatus per USP <741>. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Measurement of hydrogen ion activity in a 1% w/v aqueous suspension using calibrated glass electrode pH meter. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder size distribution based on light scattering patterns generated by dispersed particles in air. |
| Microbial Contamination | Membrane Filtration | Quantitative enumeration of aerobic microorganisms using filtration, membrane transfer to agar media, and colony counting per USP <61>. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 124–128°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.