China Factory Direct
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| CAS number | 851179-00-5 |
| Product name | 3-Chloro-2,5-difluoropyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of anticancer, antiviral, or central nervous system drugs | Pyridine ring structure introduced via nucleophilic substitution or coupling reactions to construct active molecular scaffolds |
| Agrochemicals | Synthesis of fluorinated pyridine-based insecticides or herbicides | Reaction with amines, alcohols, or thiols to generate biologically active derivatives |
| Materials Science | Building block for fluorinated functional materials or liquid crystal monomer precursors | Halogen sites utilized in cross-coupling reactions such as Suzuki or Buchwald–Hartwig couplings |
| Organic Synthesis | General building block for polyfunctionalized pyridine derivatives | Selective substitution of chlorine or fluorine atoms to achieve regioselective functionalization |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | GC-FID or GC-MS | Quantitative determination by comparing peak area of analyte to that of a reference standard using gas chromatography with flame ionization or mass spectrometric detection. |
| Related Substances | GC-FID or HPLC-UV | Separation and quantification of impurities based on retention time and UV absorbance or FID response relative to the main peak. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents by headspace or direct injection GC with FID detection. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generated in situ to react stoichiometrically with water in the sample. |
| Chloride Ion Impurity | Ion Chromatography (IC) | Separation of anions on an ion-exchange column followed by conductivity detection for quantitative chloride measurement. |
| Heavy Metals | ICP-OES | Multi-element detection after acid digestion by measuring characteristic atomic emission wavelengths in inductively coupled plasma. |
| Acidity/Alkalinity | Acid-Base Titration | Neutralization of acidic or basic impurities with standardized NaOH or HCl solution using phenolphthalein or methyl red indicator. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against standard references under controlled lighting conditions. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid using calibrated capillary apparatus. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue remaining after high-temperature ashing of the sample. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light caused by chiral compounds in solution. |
| Bulk Density | Tap Density Tester | Determination of mass per unit volume after controlled tapping of a known mass in a graduated cylinder. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless to yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.