Adenosine, N-acetyl-3',5'-O-[1,1,3,3-tetrakis(1-Methylethyl)-1,3-disiloxanediyl]- Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 85335-73-5 |
| Product name | Adenosine, N-acetyl-3',5'-O-[1,1,3,3-tetrakis(1-Methylethyl)-1,3-disiloxanediyl]- |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 85335-73-5
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 85335-73-5 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 85335-73-5
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Synthesis intermediate for nucleoside-based antiviral and anticancer drugs | Used as a protected cytidine monomer in solid-phase or solution-phase oligonucleotide synthesis to construct sequence-specific DNA/RNA analogs |
| Biotechnology | Chemical synthesis of modified oligonucleotide probes and aptamers | Enables regioselective reactions by protecting the 2′-OH group with a TIPS group and the 4-NH₂ group with an acetyl (AC) group prior to phosphodiester bond coupling |
| Diagnostics Reagent Development | Custom synthesis of high-specificity molecular diagnostic probes (e.g., for qPCR and NGS library construction) | Automated solid-phase synthesis via the phosphoramidite method, where TIPS provides acid stability and AC provides base stability to facilitate subsequent deprotection |
Manufacturing Quality Control of 85335-73-5
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 280 nm. |
| Related Substances | HPLC-UV | Separation and quantification of structurally related impurities using gradient reversed-phase HPLC with UV detection. |
| Residual Solvents | GC-FID | Detection and quantification of volatile organic solvents based on retention time and flame ionization response relative to calibration standards. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generated in situ to react stoichiometrically with water in the sample. |
| Heavy Metals | ICP-MS | Multi-element quantification of trace metal contaminants via plasma ionization and mass spectrometric detection. |
| Chloride Content | Ion Chromatography | Separation and conductivity-based quantification of chloride anions using anion-exchange column and suppressed conductivity detection. |
| Residual Catalyst (Pd) | ICP-OES | Quantification of palladium residues by measuring atomic emission intensity at characteristic wavelengths after acid digestion. |
| Optical Rotation | [alpha]D Measurement | Determination of specific rotation using a polarimeter at 20 degrees C and sodium D-line (589 nm) to confirm chiral integrity. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution based on angular dependence of laser light scattering from a dispersed sample. |
| Microbial Contamination | Membrane Filtration | Enumeration of aerobic microorganisms by filtration, membrane transfer to culture medium, and colony counting after incubation. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determination of hydrogen ion activity using a calibrated glass electrode and reference electrode in a 1% w/v aqueous solution. |
| Loss on Drying | Gravimetric Analysis | Measurement of weight loss after drying under controlled temperature and vacuum to determine volatile and moisture content. |
Technical Specifications of 85335-73-5
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 185–189°C |
| Optical Rotation | -25.0 to -29.0° (c=1, in DMF) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 85335-73-5
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 85335-73-5
Packaging of 85335-73-5
Industrial 85335-73-5 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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