4-CHLORO-3-METHOXYBENZOIC ACID Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 85740-98-3 |
| Product name | 4-CHLORO-3-METHOXYBENZOIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for 4-CHLORO-3-METHOXYBENZOIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-CHLORO-3-METHOXYBENZOIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-CHLORO-3-METHOXYBENZOIC ACID
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate in the synthesis of the herbicide quizalofop-ethyl | Multi-step organic synthesis—including esterification, acid chloride formation, and Grignard reaction—to convert 4-chloro-3-methoxybenzoic acid into the phenoxypropionate structure of quizalofop |
| Pharmaceuticals | Side-chain precursor for the antiplatelet drug ticagrelor | Amidation, chiral resolution, and coupling reactions to construct the chloromethoxybenzoyl-substituted pyrimidine side chain of ticagrelor |
| Dyes | Light-stabilizing additive component for azo and reactive dyes | Substituted benzoic acid derivative serving as a diazo component; introduction of chlorine and methoxy groups during coupling enhances color fastness and photostability |
Manufacturing Quality Control of 4-CHLORO-3-METHOXYBENZOIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time matching and threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., methanol, toluene, ethyl acetate) against calibrated standards. |
| Heavy Metals | ICP-OES | Simultaneous multi-element detection of Pb, Cd, Hg, As, and others after acid digestion, based on atomic emission intensity at characteristic wavelengths. |
| Chloride Content | Potentiometric Titration | Direct titration with silver nitrate using a silver indicator electrode; endpoint determined by potential inflection corresponding to AgCl precipitation. |
| Moisture Content | Karl Fischer Coulometric Titration | Electrochemical generation of iodine in anhydrous medium; water content calculated from total charge required to maintain stoichiometric iodine concentration. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which solid transitions to liquid, measured via capillary tube under controlled heating rate per USP <741>. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after high-temperature ashing (700-800 C) and cooling in desiccator, expressed as weight percent. |
| pH of Aqueous Suspension | pH Meter | Measurement of hydrogen ion activity in a saturated aqueous suspension (1:10 w/v) using calibrated glass electrode system per EP 2.2.3. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity versus angle to derive volume-based particle size distribution in dispersed slurry. |
| Specific Optical Rotation | Polarimeter | Measurement of rotation angle of plane-polarized light passing through a solution in a standardized cell, reported as deg * mL / (g * dm). |
| Total Organic Carbon (TOC) | Combustion-NDIR | High-temperature catalytic oxidation of organic carbon to CO2, followed by non-dispersive infrared detection and quantification against carbon standard. |
Technical Specifications of 4-CHLORO-3-METHOXYBENZOIC ACID
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 142–146 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of 4-CHLORO-3-METHOXYBENZOIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-CHLORO-3-METHOXYBENZOIC ACID
Safety Information of 4-CHLORO-3-METHOXYBENZOIC ACID
| Pictograms |   |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 4-CHLORO-3-METHOXYBENZOIC ACID
Industrial 4-CHLORO-3-METHOXYBENZOIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply