China Factory Direct
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| CAS number | 85909-04-2 |
| Product name | 4-[[(1,1-dimethylethoxy)carbonyl]amino]Butanoic acid methyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Synthesis of peptide and protein therapeutics | Serves as a Boc-protected GABA derivative monomer for solid-phase or solution-phase peptide synthesis to construct specific amino acid sequences. |
| Pharmaceutical Chemicals | Preparation of pharmaceutical intermediates | Acts as a key synthetic building block in the synthesis of GABA-derived neurological drugs such as pregabalin. |
| Biochemistry | Synthesis of biochemical probes and labeling agents | Used to synthesize bioactive molecules bearing specific functional groups, introducing the GABA structural motif as a linker or spacer group. |
| Organic Synthesis | Protecting group chemistry | Leverages the controllable deprotection of the Boc group to construct libraries of linear fatty acid esters bearing protected primary amines, enabling subsequent derivatization reactions such as amination and reduction. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time relative to reference standards or threshold reporting. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, THF, DMF) based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generation in pyridine-free reagent; measures water via stoichiometric reaction with iodine and sulfur dioxide. |
| Heavy Metals | ICP-MS | Multi-element detection after acid digestion; quantifies metals (e.g., Pb, Cd, Ni, Fe) by mass-to-charge ratio with isotopic resolution and low detection limits. |
| Chloride Content | Ion Chromatography | Separation of anions on anion-exchange column with suppressed conductivity detection; quantifies chloride as a common inorganic impurity. |
| Residual BOC Protecting Group | HPLC-UV | Specific assay for di-tert-butyl dicarbonate (Boc2O) and tert-butanol degradation products using isocratic HPLC-UV. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific rotation using sodium D-line light source to confirm chiral integrity and absence of racemization. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by observing solid-to-liquid phase change in capillary tube under controlled heating rate. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting conditions. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determination of hydrogen ion activity in a saturated aqueous suspension using calibrated glass electrode and pH meter. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue remaining after high-temperature ashing (700-800 C) to quantify non-volatile inorganic impurities. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Melting Point | 48–52°C |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.