1-(5-Bromo-4-methylthiophen-2-yl)ethanone Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 859199-06-7 |
| Product name | 1-(5-Bromo-4-methylthiophen-2-yl)ethanone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeElectronic GradeMaterial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-(5-Bromo-4-methylthiophen-2-yl)ethanone
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-(5-Bromo-4-methylthiophen-2-yl)ethanone Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-(5-Bromo-4-methylthiophen-2-yl)ethanone
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Structural building block for synthesizing active compounds, including antitumor and antiviral agents | Serves as a key intermediate in transition-metal-catalyzed coupling reactions—such as Suzuki and Heck couplings—to construct thienyl-based heterocyclic drug scaffolds |
| Organic Optoelectronic Materials | Functional building unit for hole-transport or emissive layers in organic light-emitting diodes (OLEDs) and organic field-effect transistors (OFETs) | Undergoes regioselective functionalization (e.g., borylation, amination) via the bromine atom, followed by cross-coupling to introduce conjugated side chains for tuning energy levels and charge-carrier mobility |
| Agrochemical R&D | Heterocyclic pharmacophore in novel insecticidal or fungicidal molecules | Acts as a bromothiophene precursor in nitrogen/oxygen-containing heterocycle annulation reactions to build biologically active polyheterocyclic agrochemical lead compounds |
Manufacturing Quality Control of 1-(5-Bromo-4-methylthiophen-2-yl)ethanone
| Test Item | Common Test Methods | Method Summary |
|---|---|---|
| Appearance and Physical State | Visual Inspection / Microscopic Observation | Observe the color, state (e.g., white to light yellow crystalline powder), and presence of foreign matter using the naked eye or microscope. |
| Identification | Infrared Spectroscopy (IR) | Determine the infrared absorption spectrum of the sample and compare characteristic absorption peaks (e.g., C=O, C–Br, thiophene ring functional groups) with standard spectra. |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Confirm the chemical shifts, integral ratios, and coupling constants of protons in the molecular structure via ¹H NMR spectrum to verify the compound's structure. | |
| Purity | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with methanol/water or acetonitrile/water as the mobile phase and a UV detector (e.g., 254 nm) to determine the percentage area of the main peak for purity assessment. |
| Gas Chromatography (GC) (if applicable) | For samples with certain volatility and thermal stability, GC can be used for purity analysis, but note that the compound may decompose under heat. | |
| Assay | HPLC External Standard Method / Internal Standard Method | Quantitatively determine the content of 2-Acetyl-5-bromo-4-methylthiophene by comparing with a standard of known concentration (typically ≥98.0%). |
| Residual Solvents | Gas Chromatography with Headspace Injection (HS-GC) | Detect residual organic solvents (e.g., dichloromethane, toluene, ethanol) from synthesis or purification processes, in compliance with ICH Q3C limits. |
| Water Content | Karl Fischer Titration | Determine the water content in the sample using volumetric or coulometric methods, controlled within specified limits (e.g., ≤0.5%). |
| Melting Point | Melting Point Apparatus | Determine the melting temperature range of the sample and compare with literature values (approximately 70–75°C, with slight variation between batches) to assist in purity assessment. |
| Heavy Metals | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | Detect residual heavy metal elements such as lead, cadmium, mercury, and arsenic, in compliance with pharmacopoeia or customer specified limits (e.g., ≤10 ppm). |
| Related Substances (Impurities) | HPLC Gradient Elution Method | Use a gradient elution program to separate and detect process-related impurities and degradation products. Individual impurity levels are typically ≤0.5%, and total impurities ≤1.0%. |
Technical Specifications of 1-(5-Bromo-4-methylthiophen-2-yl)ethanone
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 65-69°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-(5-Bromo-4-methylthiophen-2-yl)ethanone
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-(5-Bromo-4-methylthiophen-2-yl)ethanone
Safety Information of 1-(5-Bromo-4-methylthiophen-2-yl)ethanone
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 1-(5-Bromo-4-methylthiophen-2-yl)ethanone
Industrial 1-(5-Bromo-4-methylthiophen-2-yl)ethanone Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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