China Factory Direct
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| CAS number | 86-59-9 |
| Product name | 8-Quinolinecarboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Antibacterial drug intermediate for synthesizing quinolone antibiotics (e.g., cinoxacin) | Converted to acyl chloride via reaction with thionyl chloride, followed by condensation with amines |
| Agrochemicals | Intermediate for fungicides and insecticides | Participates in heterocyclic coupling reactions to construct quinoline-containing active molecules |
| Materials Science | Ligand for metal–organic frameworks (MOFs), used in gas adsorption and separation materials | Acts as a bidentate chelating ligand coordinating with transition metals (e.g., Zn²⁺, Cu²⁺) to assemble MOFs |
| Analytical Chemistry | Fluorescent probe and reagent for metal ion detection | Forms stable fluorescent complexes with Al³⁺, Mg²⁺, etc., for colorimetric/fluorometric analysis |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC with UV detection | Quantitative determination based on peak area comparison against a certified reference standard using reversed-phase chromatography. |
| Loss on Drying (LOD) | Gravimetric thermogravimetry | Mass loss measured after drying at 105 °C to constant weight, indicating volatile impurities and residual solvents. |
| Residue on Ignition (Sulfated Ash) | Gravimetric sulfated ash assay | Inorganic residue quantified after high-temperature incineration with sulfuric acid treatment. |
| Heavy Metals (as Pb) | ICP-OES or AAS | Total heavy metal content determined by atomic emission or absorption spectroscopy after acid digestion. |
| Chloride Impurity | Potentiometric titration with AgNO₃ | Quantification of chloride ions via precipitation titration using silver nitrate and a silver indicator electrode. |
| Related Substances | HPLC with gradient elution and UV detection | Separation and quantification of structurally similar impurities using optimized reversed-phase chromatographic conditions. |
| Melting Point | Capillary melting point apparatus | Thermal transition temperature range determined by controlled heating of crystalline sample in capillary tube. |
| Water Content (KF) | Karl Fischer coulometric titration | Electrochemical quantification of water content based on iodine generation and stoichiometric reaction with water. |
| pH of Aqueous Suspension | pH meter measurement | Acidity/basicity assessed by measuring the pH of a defined suspension (e.g., 1% w/v) in purified water. |
| Solvent Residues (e.g., MeOH, EtOAc) | GC-FID | Identification and quantification of residual organic solvents using gas chromatography with flame ionization detection. |
| Particle Size Distribution | Laser diffraction analysis | Determination of particle size distribution by measuring angular variation in laser light scattering intensity. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral molecules in solution. |
| Microbial Contamination | Membrane filtration and plate count | Quantification of aerobic microorganisms per pharmacopeial methods (e.g., USP <61>). |
| Test Item | Specification |
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| Appearance | Brown solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 165–169 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.