China Factory Direct
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| CAS number | 86-81-7 |
| Product name | 3,4,5-Trimethoxybenzaldehyde |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty GradeIndustrial GradeCosmetic GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of antibacterial drug intermediates | Introduction of specific functional groups via substitution reactions |
| Pharmaceuticals | Preparation of cardiovascular drug intermediates | Generation of target compounds through reduction, condensation, and related steps |
| Pesticides | Key intermediate in herbicide production | Coupling reactions leveraging its methoxy structure |
| Fine fragrances | Synthesis of vanillin derivatives | Production of aromatic compounds via oxidation or esterification |
| Advanced materials | Monomer for optoelectronic materials | Formation of functional polymers via polymerization |
| Dyes | Dye intermediate | Preparation of dye precursors via sulfonation or nitration |
| Test Item | Common Testing Methods | Method Overview |
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| Appearance and Characteristics | Visual inspection, Melting point determination | Observe sample color, crystal form, and whether agglomeration occurs; determine melting point range (literature value: approximately 68–71°C) to assess purity and crystalline state. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a C18 column with methanol-water or acetonitrile-water as the mobile phase, detect with a UV detector (λ = 280 nm), and quantify using the external standard method to accurately determine the main component content (typically required ≥98%). |
| Impurity Analysis | High-Performance Liquid Chromatography (HPLC) | Use the same conditions as the assay; compare impurity peak areas with the main peak area to control known impurities (e.g., 3,4,5-trimethoxybenzoic acid, unreacted starting materials) and total unknown impurities (e.g., ≤0.5%). |
| Residual Solvents | Gas Chromatography (GC) | Use headspace or direct injection with a polar column such as DB-624 and an FID detector to detect residual solvents (e.g., methanol, ethanol, dichloromethane), in compliance with ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Utilize the iodine-sulfur dioxide-pyridine-methanol system that reacts quantitatively with water; measure water content via potentiometric or coulometric methods, typically requiring ≤0.5% (w/w). |
| Melting Point | Capillary Melting Point Apparatus | Load the sample into a capillary tube, heat at a rate of 1–2°C/min, and record the temperature range from the onset of melting to complete liquefaction; compare with the standard value (68–71°C) to assess purity. |
| UV-Visible Absorption Spectroscopy | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Prepare a solution in ethanol or methanol, scan wavelengths from 200–400 nm, determine the maximum absorption wavelength (λmax ≈ 280 nm) and absorbance for qualitative confirmation and concentration estimation. |
| Chlorides, Heavy Metals | Chinese Pharmacopoeia General Methods (e.g., Chloride Test, Heavy Metals Test) | Chlorides: Add silver nitrate reagent and compare turbidity with a standard sodium chloride solution; Heavy metals: Add thioacetamide reagent in a pH 3.5 buffer solution and compare color intensity, controlling limits (e.g., ≤10 ppm). |
| Water-Soluble Impurities | Thin-Layer Chromatography (TLC) | Use silica gel plates with a mobile phase such as ethyl acetate:n-hexane (1:1), develop with a reagent (e.g., vanillin-sulfuric acid), and observe the number and intensity of impurity spots as a rapid screening method. |
| Gas Chromatography-Mass Spectrometry (GC-MS) | GC-MS | Used for structural identification of unknown impurities; confirm degradation products or synthetic by-products (e.g., methoxy-substituted isomers) by matching mass spectra against reference libraries, suitable for R&D and abnormal investigations. |
| Test Item | Specification |
|---|---|
| Appearance | White to light yellow powder or lumps |
| Purity | >=98.5% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 78-82°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Identification (NMR) | Conforms to reference standard |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.