Ethyl L-thiazolidine-4-carboxylate hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 86028-91-3 |
| Product name | Ethyl L-thiazolidine-4-carboxylate hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Ethyl L-thiazolidine-4-carboxylate hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Ethyl L-thiazolidine-4-carboxylate hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Ethyl L-thiazolidine-4-carboxylate hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a chiral intermediate for synthesizing sulfur-containing amino acid derivatives or peptide-based drugs | Integrated into multistep drug synthesis pathways via organic reactions such as esterification and condensation to introduce specific molecular structures |
| Chemical Synthesis | Employed as a chiral auxiliary or ligand precursor in asymmetric synthesis | Provides a chiral environment in transition metal-catalyzed reactions to enable stereoselective transformations |
| Biochemical Research | Used to construct peptide segments mimicking sulfur-containing proline residues for studying protein conformation–function relationships | Served as a building block in solid-phase or liquid-phase peptide synthesis (SPPS/LPPS) to assemble custom peptide chains |
| Medicinal Chemistry | Applied in the development of antiviral, antibacterial, or antitumor active compounds | Utilized as a key building block; structural modifications followed by biological activity screening |
Manufacturing Quality Control of Ethyl L-thiazolidine-4-carboxylate hydrochloride
| Detection Item | Common Testing Method | Method Overview |
|---|---|---|
| Identification Test | Infrared Spectroscopy (IR) | Determines the infrared absorption spectrum of the sample and compares it with a reference spectrum to confirm the presence of characteristic functional groups in L-thioproline ethyl ester hydrochloride (e.g., C=O, N–H, S–C). |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Utilizes nuclear magnetic resonance technology to analyze chemical shifts and coupling constants of hydrogen atoms, verifying structural characteristics of the target compound. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with an appropriate mobile phase (e.g., phosphate buffer-acetonitrile system) for gradient or isocratic elution. The main component is quantified using a UV detector (typically at 200–210 nm). |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Similar to content determination, but chromatographic conditions are optimized to achieve good separation between the main peak and potential impurities (e.g., starting materials, intermediates, degradation products). Impurity levels are calculated using area normalization or the principal component self-control method with correction factors. |
| Moisture Content | Karl Fischer Titration | Based on the quantitative reaction between iodine and sulfur dioxide in the presence of pyridine/imidazole with water. Moisture content is accurately determined using coulometric or volumetric Karl Fischer titration. |
| Residual Solvents | Gas Chromatography (GC) | Uses headspace injection or direct injection with polar or non-polar capillary columns and FID detection to identify and quantify organic solvents (e.g., methanol, ethanol, dichloromethane, ethyl acetate) potentially residual from synthesis. |
| Heavy Metals | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | After sample digestion, ICP-MS or AAS is used to determine the residual levels of heavy metals such as lead, arsenic, cadmium, and mercury, ensuring compliance with pharmacopoeial limits. |
| pH Value | pH Meter Method | A solution of specified concentration (e.g., 1% w/v) is prepared, and its acidity or alkalinity is measured using a calibrated pH meter, reflecting the dissociation properties of the hydrochloride salt and possible influence from impurities. |
| Specific Rotation | Polarimetry | Measures the optical rotation of a solution at a defined wavelength (usually sodium D line, 589 nm) and temperature, then calculates specific rotation to verify L-configuration purity and optical activity. |
| Drying Loss | Thermogravimetric Analysis (TGA) or Constant Temperature Drying Method | The sample is dried at a specified temperature (e.g., 105°C) until constant weight is achieved. The percentage of mass loss is calculated to assess volatile components, including moisture and low-boiling impurities. |
Technical Specifications of Ethyl L-thiazolidine-4-carboxylate hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (by NMR) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -81° to -77° (c=1, in 1M HCl) |
| Melting Point | 148°C to 152°C |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Ethyl L-thiazolidine-4-carboxylate hydrochloride
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| Lot/Batch Number | *Required fields | |
NMR Spectra of Ethyl L-thiazolidine-4-carboxylate hydrochloride
Safety Information of Ethyl L-thiazolidine-4-carboxylate hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Ethyl L-thiazolidine-4-carboxylate hydrochloride
Industrial Ethyl L-thiazolidine-4-carboxylate hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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