China Factory Direct
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| CAS number | 86060-87-9 |
| Product name | FMOC-VAL-OPFP |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Amino acid protecting reagent for peptide synthesis | Used as the Fmoc-protected derivative of valine (Val) in solid-phase peptide synthesis (SPPS) to introduce valine residues via coupling to the amino group on resin |
| Biochemical Research | Synthesis of custom peptides containing valine | Employed as a building block in organic synthesis; the Fmoc protecting group is selectively removed under mild basic conditions to enable controlled coupling |
| Pharmaceutical Intermediate Manufacturing | Key intermediate for preparing therapeutic peptides or peptidomimetics | Participates in amide bond formation reactions with activators (e.g., HBTU/DIPEA) in anhydrous organic solvents such as DMF |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., DMF, DCM, EtOAc) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, using isotopic detection for high sensitivity and selectivity. |
| Chloride Content | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract; quantified against sodium chloride calibration curve. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific rotation using sodium D-line light source at specified concentration, temperature, and path length to confirm chiral integrity. |
| Residual Palladium | ICP-OES | Quantification of Pd after microwave-assisted acid digestion using plasma optical emission spectroscopy at characteristic wavelengths. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion via laser scattering to determine D10, D50, D90 values per USP <429>. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | pH determination of 1% w/v suspension in water using calibrated pH electrode and buffer standards. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) per USP <61> and <62>. |
| Loss on Drying | Gravimetric Thermogravimetry | Mass loss measured after drying at 105 C for 2 hours under controlled humidity; reported as weight percent. |
| Test Item | Specification |
|---|---|
| Appearance | White powder |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | -23±2° (c=1, in CHCl3) |
| Melting Point | 75–79°C |
| Identification (NMR) | Conforms to reference spectrum |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.