China Factory Direct
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| CAS number | 86087-23-2 |
| Product name | (S)-(+)-3-Hydroxytetrahydrofuran |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral synthetic intermediate for antiviral agents (e.g., HIV protease inhibitors), antibiotics, and other chiral active pharmaceutical ingredients (APIs) | Used as a chiral building block in asymmetric synthesis, cyclization, or functional group transformations to construct oxygen-containing heterocyclic structures |
| Agrochemicals | Intermediate for synthesizing chiral pesticides or plant growth regulators | Introduces stereospecific functional groups via nucleophilic substitution, oxidation, or reduction |
| Fine Chemicals | Precursor for chiral ligands, catalysts, or functional materials | Applied in constructing stereoselective catalytic systems or high-value fine chemicals |
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Identification Test | Infrared Spectroscopy (IR) Proton Nuclear Magnetic Resonance (¹H NMR) |
Confirm the structural characteristics and stereochemical configuration of (S)-(+)-3-hydroxytetrahydrofuran by comparing characteristic absorption peaks in IR spectra or chemical shifts in ¹H NMR with reference spectra. |
| Optical Purity / Enantiomeric Excess (e.e.) | Chiral High-Performance Liquid Chromatography (Chiral HPLC) Chiral Gas Chromatography (Chiral GC) |
Separate enantiomers using chiral stationary phase columns; calculate the content of the (S)-enantiomer based on peak areas to assess optical purity (typically requiring e.e. ≥98%). |
| Content Determination | Gas Chromatography (GC) High-Performance Liquid Chromatography (HPLC) |
Quantify the main component using internal or external standard methods based on chromatographic peak area, ensuring product purity meets quality specifications (e.g., ≥98.0%). |
| Water Content | Karl Fischer Titration | Determine trace moisture content quantitatively using Karl Fischer reagent, which reacts specifically with water in the sample (typically requiring ≤0.5%). |
| Residual Solvents | Headspace Gas Chromatography (Headspace GC) | Identify potentially residual organic solvents (e.g., methanol, ethanol, dichloromethane) via headspace sampling combined with GC analysis, complying with ICH Q3C guidelines. |
| Related Substances / Impurities | Gas Chromatography (GC) High-Performance Liquid Chromatography (HPLC) |
Separate and detect process impurities and degradation products using gradient elution or programmed temperature ramping; individual impurities are typically controlled at ≤0.1%, with total impurities ≤0.5%. |
| Specific Rotation | Polarimeter Measurement | Determine the specific rotation of the sample solution under specified wavelength (usually sodium D line, 589 nm) and temperature to verify its chiral properties and purity (e.g., [α]²⁵D = +20° to +24°). |
| Test Item | Specification |
|---|---|
| Appearance | Colorless to light yellow clear liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +17.0 to +20.0 deg (c=1, in CHCl3) |
| Refractive Index (n20/D) | 1.452 to 1.456 |
| Relative Density (20°C/25°C) | 1.075 to 1.085 g/cm³ |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.