Ethyl all cis-5,8,11,14,17-Eicosapentaenoate Bulk Supply for Industrial Use

China Factory Direct
CAS number 86227-47-6
Product name Ethyl all cis-5,8,11,14,17-Eicosapentaenoate
Stock Stock readily available; annual supply capacity exceeding 1,000 tons.
Grade Pharmaceutical Grade
Packaging 25L/drum
Sample Test Samples Available (Click to Request Samples)
COA View COA
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Supply Type Bulk / Contract manufacturing / OEM
Shipping FCL / LCL available
Payment Terms Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C).
Manufacturer Greenrock Chemical(China Factory)
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Documents We Provide for Ethyl all cis-5,8,11,14,17-Eicosapentaenoate

COA TDS SDS NMR MOA Certificate of Origin Transport Report TSCA Declaration Production Flow Chart
Pre-sale: Only COA, SDS and NMR are available.
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Ethyl all cis-5,8,11,14,17-Eicosapentaenoate Supplier from China

17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.

Industrial Applications of Ethyl all cis-5,8,11,14,17-Eicosapentaenoate

Industry Application Process
Food Industry Nutritional fortificant for food Synthesized directly or purified from fish oil
Pharmaceutical Industry Preparation of pharmaceutical intermediates Purified via chemical synthesis or natural extraction

Manufacturing Quality Control of Ethyl all cis-5,8,11,14,17-Eicosapentaenoate

Test Item Common Testing Method Method Overview
Content Determination Gas Chromatography (GC) Capillary column gas chromatography is used to determine the content of cis-20:5 ethyl ester by internal or external standard method. The sample is silylated and injected, with retention time for qualitative analysis and peak area for quantitative analysis. Suitable for high-purity sample analysis.
High-Performance Liquid Chromatography (HPLC-ELSD/UV) Reverse-phase C18 chromatographic column is used, with mobile phase commonly being acetonitrile-water or methanol-water system, combined with evaporative light scattering detector (ELSD) or low-wavelength UV detector. No derivatization required, suitable for thermally unstable samples.
Impurity Analysis Gas Chromatography-Mass Spectrometry (GC-MS) Used to identify and quantify organic impurities, isomers, and degradation products in cis-20:5 ethyl ester. Structural identification is performed using mass spectral library. High sensitivity and specificity.
High-Performance Liquid Chromatography-Mass Spectrometry (HPLC-MS) More suitable for the analysis of non-volatile or thermally unstable impurities, enabling accurate identification of oxidation products, residual glycerides, and other impurities.
Cis Configuration Confirmation Nuclear Magnetic Resonance Spectroscopy (¹H-NMR and ¹³C-NMR) The cis configuration (e.g., 5Z,8Z,11Z,14Z,17Z) is confirmed through characteristic chemical shifts and coupling constants. Provides direct molecular structure evidence, used for reference standards or key batch confirmation.
Ultraviolet-Visible Spectrophotometry (UV-Vis) The conjugated double bond system's characteristic absorption peaks at 200–220 nm are used to assess unsaturation degree, assisting in identifying the presence of a polyunsaturated structure, but cannot confirm the configuration alone.
Peroxide Value (Oxidation Degree) Titration Method (Iodometric Method) Based on the reaction of peroxides with potassium iodide to release iodine, the peroxide value is calculated by titrating with sodium thiosulfate. Used to evaluate the oxidation level of the sample, suitable for raw material and storage stability testing.
Acid Value Acid-Base Titration Method The sample is dissolved in an organic solvent (e.g., ethanol-ether mixture), and free fatty acids are titrated with standardized potassium hydroxide solution to reflect the esterification degree or hydrolysis condition.
Esterification Degree Gas Chromatography or HPLC The ratio of free fatty acids to esterified forms is compared to evaluate whether ethyl esterification is complete. Alternatively, the esterification rate can be calculated from the difference between saponification value and acid value.
Moisture Content Karl Fischer Method An electrochemical reaction is used to quantitatively determine moisture content in the sample. It includes volumetric and coulometric methods, with high sensitivity suitable for trace moisture detection.
Residual Solvents Gas Chromatography (GC) According to pharmacopoeia methods (e.g., Chinese Pharmacopoeia, USP), detect residual organic solvents used in production (e.g., methanol, ethanol, hexane) to ensure compliance with safety limits.
Microbial Limit Microbial Limit Test Method Aerobic bacterial count, mold and yeast count, and controlled bacteria (e.g., Escherichia coli, Salmonella) are tested according to pharmacopoeia requirements to ensure microbial safety of the product.
Heavy Metals Atomic Absorption Spectrometry (AAS) or ICP-MS Detect heavy metal residues such as lead, arsenic, mercury, and cadmium. ICP-MS has higher sensitivity and can simultaneously detect multiple elements, suitable for controlling high-purity pharmaceutical-grade products.

Technical Specifications of Ethyl all cis-5,8,11,14,17-Eicosapentaenoate

Test Item Specification
Appearance Colorless to pale yellow clear liquid
Purity >=98.5%
Water Content (KF) <=0.5%
Total Impurities <=1.5%
Single Impurity <=0.5%
Acid Value (mg KOH/g) <=1.0
Refractive Index (n20/D) 1.482–1.488
Relative Density (20°C/25°C) 0.875–0.885 g/cm³
Odor Characteristic fatty odor
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com

Download COA of Ethyl all cis-5,8,11,14,17-Eicosapentaenoate

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NMR Spectra of Ethyl all cis-5,8,11,14,17-Eicosapentaenoate

Safety Information of Ethyl all cis-5,8,11,14,17-Eicosapentaenoate

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Safety Data Sheet

Packaging of Ethyl all cis-5,8,11,14,17-Eicosapentaenoate

We have a diverse range of chemicals in stock. Available in IBC (1000 ltr.), Drums (200 ltr.),Drums (25 ltr.).

Industrial Ethyl all cis-5,8,11,14,17-Eicosapentaenoate Procurement FAQ

1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.

2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.

3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.

4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.

5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.

6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.

7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.

8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.

9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.

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