China Factory Direct
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| CAS number | 862574-88-7 |
| Product name | 1-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-cyclopropanecarboxylicacid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate in the synthesis of certain pesticides | Chemical synthesis |
| Pharmaceuticals | Preparation of biologically active compounds, including drug molecules | Chemical synthesis, structural modification |
| Fine chemicals | Base raw material for synthesizing other organic compounds | Chemical synthesis |
| Test Item | Common Test Methods | Method Overview |
|---|---|---|
| Identity | Infrared Spectroscopy (IR) | Compare the sample's infrared absorption spectrum with reference spectra to confirm the presence of characteristic functional groups (e.g., carboxylic acid, C–F, acetal, etc.). |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Analyze chemical shifts, coupling constants, and integration areas of hydrogen atoms to verify molecular structural features. | |
| Mass Spectrometry (MS or HRMS) | Determine molecular ion peaks and fragment ions to confirm molecular weight and elemental composition; high-resolution MS can verify molecular formula. | |
| Assay | High-Performance Liquid Chromatography (HPLC-UV) | Use a reversed-phase C18 column with an appropriate mobile phase (e.g., acetonitrile/water + buffer salt) under gradient elution, and quantify the main component using a UV detector. |
| Gas Chromatography (GC, if applicable) | If the compound is sufficiently volatile and thermally stable, it may be derivatized and quantified using GC-FID or GC-MS. | |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC-DAD/UV) | Combine forced degradation studies (acid, base, oxidation, heat, light) with HPLC separation to detect and quantify process impurities and degradation products. |
| Ultra-Performance Liquid Chromatography-Mass Spectrometry (UPLC-MS) | Enhances separation efficiency and sensitivity for qualitative and quantitative analysis of trace-level impurities. | |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Use headspace sampling technique combined with FID detection to determine residual organic solvents (e.g., methanol, acetonitrile, dichloromethane, etc.) from manufacturing processes. |
| Water Content | Karl Fischer Titration | Measure water content using volumetric or coulometric methods; suitable for compounds containing polar groups such as carboxylic acids. |
| Melting Point | Melting Point Apparatus | Determine the melting temperature range using capillary method or digital melting point apparatus; serves as one indicator of physical purity. |
| Specific Optical Rotation (if chiral) | Polarimeter | If the molecule contains chiral centers (e.g., asymmetric cyclopropane), specific optical rotation must be measured to control optical purity. |
| pH Value (solution) | pH Meter | Prepare an aqueous solution at a defined concentration and measure its pH value to reflect carboxylic acid dissociation behavior and potential influence of acidic impurities. |
| Heavy Metals | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Detect residual heavy metal elements such as lead, arsenic, cadmium, and mercury in the sample, ensuring compliance with pharmacopoeial limits. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 142–146°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Acid Value (mg KOH/g) | 220–235 mg KOH/g |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.