China Factory Direct
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| CAS number | 863329-66-2 |
| Product name | 2'-deoxy-2'-fluoro-2'-C-methyluridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Antiviral drug intermediate | Used in the synthesis of nucleoside analogues, serving as a key intermediate for direct-acting antiviral drugs targeting hepatitis C virus (HCV) infection |
| Biochemical research | Nucleotide analogue research | Applied in laboratory studies of RNA replication mechanisms and antiviral modes of action |
| Test Item | Commonly Used Testing Method | Method Overview |
|---|---|---|
| Chemical Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Analyzes chemical shifts of hydrogen, carbon, and fluorine atoms using ¹H-NMR, ¹³C-NMR, and ¹⁹F-NMR to confirm molecular framework and stereochemistry. |
| Molecular Weight and Purity Confirmation | High-Resolution Mass Spectrometry (HRMS) | Uses high-resolution mass spectrometry to accurately determine molecular ion peaks, verifying the molecular formula and presence of impurities, adducts, or degradation products. |
| Chemical Purity | High-Performance Liquid Chromatography (HPLC) | Separates components using reverse-phase or normal-phase chromatography columns with UV or evaporative light scattering detection to quantify the main component and assess related substances and total impurity levels. |
| Enantiomeric Purity / Stereoisomers | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Uses chiral stationary phase columns to separate enantiomers, ensuring the (2'R) configuration is predominant and controlling the limit of (2'S) isomer. |
| Residual Solvents | Gas Chromatography (GC) with Headspace Sampling | Based on ICH Q3C, uses capillary column separation with FID or MS detection to quantify residual organic solvents such as methanol, acetonitrile, and dichloromethane. |
| Water Content | Karl Fischer Titration | Measures trace moisture using volumetric or coulometric methods to ensure compliance with standards for loss on drying or moisture content. |
| Heavy Metals / Elemental Impurities | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Tests for potentially toxic elements like lead, arsenic, cadmium, and mercury in accordance with ICH Q3D to ensure levels are below safety thresholds. |
| Thermal Stability / Degradation Products | Forced Degradation Studies + HPLC-MS | Subjects samples to acidic, basic, oxidative, light, and high-temperature conditions and uses HPLC-MS to identify major degradation pathways and impurity structures. |
| Crystal Form Analysis | X-Ray Powder Diffraction (XRPD) | Used for solid active pharmaceutical ingredients (APIs) to identify polymorphism and ensure batch-to-batch consistency and stability of crystal form. |
| Melting Point | Capillary Melting Point Apparatus or DSC | Determines the melting temperature range as a physical constant to assist in identification and purity assessment. |
| Test Item | Specification |
|---|---|
| Appearance | White to almost white powder or crystals |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Optical Rotation | +87.0 to +92.0° (c=1, in water) |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.