China Factory Direct
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| CAS number | 863753-30-4 |
| Product name | (2-Aminophenyl)boronic acid hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Served as a synthetic intermediate for preparing boron-containing drug molecules, including protease inhibitors and anticancer compounds | Organic synthesis reactions, including Suzuki-Miyaura coupling, reductive amination, and amidation |
| Chemical Research | Used to construct benzoheterocyclic compounds and functionalized arylboronic acid derivatives | Palladium-catalyzed cross-coupling, click chemistry, and multicomponent reactions |
| Materials Science | Employed in synthesizing organic boron-based functional materials with fluorescence or sensing properties | Molecular self-assembly, coordination polymerization, and covalent organic framework (COF) construction |
| Biotechnology | Applied as a recognition unit in sugar-sensing probes or biosensors | Reversible boronic acid–cis-diol binding reaction, fluorescent labeling, and detection |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, acetone, ethyl acetate) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content based on stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion, with detection at sub-pptr levels. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode to detect endpoint based on change in potential. |
| pH (1% w/v aqueous solution) | pH Meter Measurement | Direct measurement of hydrogen ion activity in a standardized aqueous suspension using calibrated pH electrode. |
| Residue on Ignition | Gravimetric Analysis | Heating sample at 700-800 C to constant weight and determining inorganic ash content by mass difference. |
| Particle Size Distribution | Laser Diffraction | Analysis of dispersed dry powder using laser scattering to determine D10, D50, D90 values per ISO 13320. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, using calibrated digital melting point instrument. |
| Optical Rotation | [a]D Measurement | Measurement of specific rotation using sodium D-line light source in solution to assess chiral purity and identity. |
| Microbial Limits | Membrane Filtration | Quantitative assessment of aerobic microorganisms and absence of specified pathogens per USP <61> and <62>. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 175–179°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.