3,5-Difluorophenylboronic acid,pinacol ester Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 863868-36-4 |
| Product name | 3,5-Difluorophenylboronic acid,pinacol ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3,5-Difluorophenylboronic acid,pinacol ester
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3,5-Difluorophenylboronic acid,pinacol ester Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3,5-Difluorophenylboronic acid,pinacol ester
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a key intermediate in synthesizing drug molecules containing the 3,5-difluorophenyl moiety, such as kinase inhibitors and antitumor compounds | Applied in Suzuki-Miyaura coupling reactions |
| Agrochemicals | Used to construct novel fluorinated aryl-based pesticide or herbicide molecules | Applied in palladium-catalyzed cross-coupling reactions |
| Materials Science | Used to synthesize fluorinated functional organic electronic materials (e.g., hole-transport materials for OLEDs and OFETs) | Applied in Suzuki coupling polymerization or small-molecule construction |
| Chemical R&D | Used as a stable, handleable boronic acid derivative to introduce the 3,5-difluorophenyl group in organic synthesis | Applied in transmetalation followed by coupling with aryl or vinyl halides |
Manufacturing Quality Control of 3,5-Difluorophenylboronic acid,pinacol ester
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., residual phenol, boronic acid, hydrolysis products) via gradient HPLC-UV against qualified impurity standards. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., THF, toluene, methanol) using headspace GC with flame ionization detection calibrated with standard solutions. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration based on the stoichiometric reaction of iodine with water in pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pd, Ni, Fe, Cu) after acid digestion using inductively coupled plasma mass spectrometry with isotope dilution calibration. |
| Residual Boron | ICP-OES | Measures total boron content post-acid digestion via inductively coupled plasma optical emission spectroscopy at characteristic emission wavelength (249.773 nm). |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction and filtration. |
| Sulfate Content | Ion Chromatography | Separates and quantifies sulfate ions using suppressed conductivity detection following sample dissolution and centrifugation. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white light against standard reference samples. |
| Loss on Drying | Gravimetric Analysis | Measures weight loss after drying under vacuum at 60 C for 2 hours, indicating volatile and moisture content. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light in solution to confirm chiral integrity (if applicable) and detect racemization; uses sodium D-line at 20 C. |
Technical Specifications of 3,5-Difluorophenylboronic acid,pinacol ester
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 118–122°C |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3,5-Difluorophenylboronic acid,pinacol ester
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3,5-Difluorophenylboronic acid,pinacol ester
Safety Information of 3,5-Difluorophenylboronic acid,pinacol ester
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 3,5-Difluorophenylboronic acid,pinacol ester
Industrial 3,5-Difluorophenylboronic acid,pinacol ester Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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