China Factory Direct
|
|
| CAS number | 86393-33-1 |
| Product name | 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing antiviral agents (e.g., adefovir dipivoxil analogues) and antimicrobial agents | Used as a key chiral building block to construct the core active molecular structure via amidation, coupling, and related reactions |
| Agrochemicals | Intermediate for synthesizing novel insecticides and fungicides | Applied in preparing cyclopropyl-containing active ingredients, such as pyrethroid derivatives |
| Materials Science | Monomer for polymers and additive for functional materials | Introduced as a cyclopropyl side chain into polymers via ring-opening polymerization or copolymerization to enhance thermal stability and mechanical properties |
| Detection Item | Common Detection Methods | Method Overview |
|---|---|---|
| Content Assay | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with a UV detector (typically at ~210 nm), employing a mobile phase of water and organic solvent (e.g., methanol or acetonitrile) in gradient or isocratic elution to quantitatively analyze cyclopropanecarboxylic acid content. Suitable for precise determination in high-purity samples. |
| Gas Chromatography (GC) | After derivatization (e.g., esterification), separation is performed using a capillary column with FID detection. Suitable for volatile derivatives, offering high sensitivity for trace analysis. | |
| Purity Analysis | High-Performance Liquid Chromatography-Mass Spectrometry (HPLC-MS) | Combines the separation capability of HPLC with the qualitative power of MS to accurately identify the main component and impurity structures, used for high-purity assessment and impurity characterization. |
| Water Content | Karl Fischer Titration | Based on the reaction of iodine and sulfur dioxide with water in an anhydrous environment, this method precisely determines water content in samples, particularly suitable for water-sensitive organic acids. |
| Acid Value / Titration Content | Acid-Base Titration | Titrates a solution of cyclopropanecarboxylic acid in ethanol or water with standard sodium hydroxide, using phenolphthalein or potentiometric methods to indicate the endpoint, then calculates acid value or content. Simple to perform and suitable for routine quality control. |
| Organic Impurities | Gas Chromatography (GC) or HPLC | Detects potential organic by-products or residual solvents (e.g., cyclopropane derivatives, unreacted starting materials) through retention time comparison and peak area quantification. |
| Residual Solvents | Gas Chromatography (GC) | According to ICH guidelines, headspace-GC is used to detect residual organic solvents (e.g., methanol, ethanol, dichloromethane) that may remain from the manufacturing process. |
| Crystal Form / Physical Form | Differential Scanning Calorimetry (DSC) or X-ray Diffraction (XRD) | DSC analyzes melting point and thermal behavior; XRD determines crystal structure, suitable for physical characterization of solid samples. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, measures residual heavy metal elements such as lead, cadmium, mercury, and arsenic to ensure compliance with pharmaceutical or industrial safety standards. |
| Solution Clarity and Color | Visual Color Comparison or UV-Visible Spectrophotometry | The sample is dissolved at a specified concentration and compared visually with standard color solutions or measured for absorbance at specific wavelengths to assess appearance quality. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (by LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 42-46°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Odor | Characteristic odor |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.