China Factory Direct
|
|
| CAS number | 865758-96-9 |
| Product name | 2-[(6-Chloro-3,4-dihydro-3-Methyl-2,4-dioxo-1(2h)-pyriMidinyl)Methyl]benzonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of antitumor or antiviral drugs | Chemical synthesis and purification |
| Agrochemicals | Used as an active ingredient in the development of novel insecticides or herbicides | Formulation development and bioactivity testing |
| Research | Used as a reference standard in organic synthesis or medicinal chemistry research | Analytical testing and structural characterization |
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state (e.g., white to off-white powder), and check for clumping or visible impurities. |
| Identification | Fourier Transform Infrared Spectroscopy (FT-IR) | Compare the sample spectrum with the reference standard; confirm the presence of characteristic functional groups (e.g., nitrile, carbonyl, C–Cl bond) based on consistent absorption peaks for structural confirmation. |
| Nuclear Magnetic Resonance Spectroscopy (¹H-NMR / ¹³C-NMR) | Analyze chemical shifts, coupling constants, and integration areas of hydrogen and carbon atoms to verify molecular structure. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use reversed-phase columns (e.g., C18) with UV detection (typically at 254 nm or based on maximum absorption wavelength); determine active ingredient content using external standard or internal standard method. |
| Impurity Profiling | HPLC (Related Substances) | Separate process impurities, degradation products, etc., using gradient or isocratic elution; calculate peak areas of individual impurities to assess total impurity levels and individual limits. |
| Residual Solvents | Gas Chromatography (GC) | Detect organic solvents potentially remaining from manufacturing processes (e.g., methanol, ethanol, acetone, dichloromethane, acetonitrile) via headspace-GC analysis, complying with ICH Q3C guidelines. |
| Moisture Content | Karl Fischer Titration | Accurately measure water content in the sample, essential for quality control of raw materials to prevent hydrolysis and degradation. |
| Residue on Ignition | Sulfated Ash Method | After high-temperature charring followed by sulfuric acid treatment and further incineration, weigh the inorganic residue to assess inorganic impurity levels. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, determine levels of heavy metals such as lead, cadmium, mercury, and arsenic, meeting pharmacopoeial or ICH Q3D elemental impurity requirements. |
| Particle Size Distribution | Laser Diffraction Analysis (LDAs) | Used for solid raw materials; evaluate particle size distribution, which affects solubility, bioavailability, and formulation processing. |
| Polymorphic Analysis | X-Ray Powder Diffraction (XRPD) | Identify different polymorphic forms and ensure batch-to-batch consistency, as crystal form impacts stability and dissolution behavior. |
| Thermal Stability | Differential Scanning Calorimetry (DSC) | Analyze melting point, phase transitions, crystallinity, and thermal decomposition temperature to assess thermal stability. |
| Thermogravimetric Analysis (TGA) | Monitor mass changes during heating to determine solvent residues, decomposition temperatures, and other thermal behaviors. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=20 ppm |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.