China Factory Direct
|
|
| CAS number | 86728-85-0 |
| Product name | Ethyl S-4-chloro-3-hydroxybutyrate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral synthetic intermediate for manufacturing statin cholesterol-lowering drugs (e.g., atorvastatin) | Applied in asymmetric synthesis and enzyme-catalyzed reactions |
| Fine Chemicals | Synthesis of other chiral compounds or optically active materials | Applied in esterification and chiral resolution |
| Biotechnology | Substrate or chiral auxiliary in enzyme-catalyzed reactions | Applied in biocatalysis and fermentation processes |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column. |
| Enantiomeric Excess (ee) | Chiral Gas Chromatography (cGC) | Separation of R- and S-enantiomers on a chiral stationary phase; ee calculated from peak area ratio. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Volatile solvents quantified by equilibrium partitioning into headspace followed by GC-FID analysis. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration where iodine is generated in situ to react stoichiometrically with water. |
| Acid Value | Acid-Base Titration with NaOH standard solution | Neutralization of free carboxylic acid groups using standardized sodium hydroxide solution and potentiometric endpoint detection. |
| Chloride Content | Ion Chromatography (IC) with conductivity detection | Separation and quantification of chloride anions using an anion-exchange column and suppressed conductivity detection. |
| Heavy Metals (Pb, Cd, Hg, As) | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Multi-element trace metal quantification after acid digestion via plasma ionization and mass-selective detection. |
| Related Substances | High-Performance Liquid Chromatography (HPLC) with UV detection | Separation and quantification of impurities using reversed-phase C18 column and UV absorbance at 210 nm. |
| Optical Rotation | [a]D Measurement using Polarimeter | Determination of specific rotation at 589 nm (Na D-line) in solution, proportional to enantiomeric composition. |
| Residue on Ignition | Gravimetric Analysis (Sulfated Ash) | Sample ignited at 700-750 C after sulfuric acid treatment; residual inorganic ash weighed. |
| Appearance | Visual Inspection in Glass Vial under Controlled Lighting | Assessment of physical state, color, and clarity against established visual standards under daylight-equivalent illumination. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determination of hydrogen ion activity in a 1% w/v aqueous solution using calibrated glass electrode. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% (GC) |
| Optical Rotation | -16.0 to -13.0 deg (c=1, in CHCl3) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Refractive Index (n20/D) | 1.442–1.448 |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.