Ethyl S-4-chloro-3-hydroxybutyrate Bulk Supply for Industrial Use

China Factory Direct
CAS number 86728-85-0
Product name Ethyl S-4-chloro-3-hydroxybutyrate
Stock Stock readily available; annual supply capacity exceeding 1,000 tons.
Grade Pharmaceutical GradeIndustrial GradeSpecialty Grade
Packaging 25L/drum200L/drum1000L/IBC
Sample Test Samples Available (Click to Request Samples)
COA View COA
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Supply Type Bulk / Contract manufacturing / OEM
Shipping FCL / LCL available
Payment Terms Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C).
Manufacturer Greenrock Chemical(China Factory)
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Documents We Provide for Ethyl S-4-chloro-3-hydroxybutyrate

COA TDS SDS NMR MOA Certificate of Origin Transport Report TSCA Declaration Production Flow Chart
Pre-sale: Only COA, SDS and NMR are available.
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Ethyl S-4-chloro-3-hydroxybutyrate Supplier from China

17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.

Industrial Applications of Ethyl S-4-chloro-3-hydroxybutyrate

Industry Application Process
Pharmaceuticals Chiral synthetic intermediate for manufacturing statin cholesterol-lowering drugs (e.g., atorvastatin) Applied in asymmetric synthesis and enzyme-catalyzed reactions
Fine Chemicals Synthesis of other chiral compounds or optically active materials Applied in esterification and chiral resolution
Biotechnology Substrate or chiral auxiliary in enzyme-catalyzed reactions Applied in biocatalysis and fermentation processes

Manufacturing Quality Control of Ethyl S-4-chloro-3-hydroxybutyrate

Detection Item Common Analytical Method Method Overview
Assay (Purity) Gas Chromatography (GC) with FID detection Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column.
Enantiomeric Excess (ee) Chiral Gas Chromatography (cGC) Separation of R- and S-enantiomers on a chiral stationary phase; ee calculated from peak area ratio.
Residual Solvents Headspace Gas Chromatography (HS-GC) Volatile solvents quantified by equilibrium partitioning into headspace followed by GC-FID analysis.
Water Content Karl Fischer Titration (Coulometric mode) Electrochemical titration where iodine is generated in situ to react stoichiometrically with water.
Acid Value Acid-Base Titration with NaOH standard solution Neutralization of free carboxylic acid groups using standardized sodium hydroxide solution and potentiometric endpoint detection.
Chloride Content Ion Chromatography (IC) with conductivity detection Separation and quantification of chloride anions using an anion-exchange column and suppressed conductivity detection.
Heavy Metals (Pb, Cd, Hg, As) Inductively Coupled Plasma Mass Spectrometry (ICP-MS) Multi-element trace metal quantification after acid digestion via plasma ionization and mass-selective detection.
Related Substances High-Performance Liquid Chromatography (HPLC) with UV detection Separation and quantification of impurities using reversed-phase C18 column and UV absorbance at 210 nm.
Optical Rotation [a]D Measurement using Polarimeter Determination of specific rotation at 589 nm (Na D-line) in solution, proportional to enantiomeric composition.
Residue on Ignition Gravimetric Analysis (Sulfated Ash) Sample ignited at 700-750 C after sulfuric acid treatment; residual inorganic ash weighed.
Appearance Visual Inspection in Glass Vial under Controlled Lighting Assessment of physical state, color, and clarity against established visual standards under daylight-equivalent illumination.
pH of Aqueous Solution Potentiometric pH Measurement Determination of hydrogen ion activity in a 1% w/v aqueous solution using calibrated glass electrode.

Technical Specifications of Ethyl S-4-chloro-3-hydroxybutyrate

Test Item Specification
Appearance Colorless liquid
Purity >=98.0% (GC)
Optical Rotation -16.0 to -13.0 deg (c=1, in CHCl3)
Water Content (KF) <=0.5%
Total Impurities <=2.0%
Single Impurity <=0.5%
Identification (NMR) Conforms to reference spectrum
Refractive Index (n20/D) 1.442–1.448
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com

Download COA of Ethyl S-4-chloro-3-hydroxybutyrate

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NMR Spectra of Ethyl S-4-chloro-3-hydroxybutyrate

Safety Information of Ethyl S-4-chloro-3-hydroxybutyrate

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Signal Word Danger
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Packaging of Ethyl S-4-chloro-3-hydroxybutyrate

We have a diverse range of chemicals in stock. Available in IBC (1000 ltr.), Drums (200 ltr.),Drums (25 ltr.).

Industrial Ethyl S-4-chloro-3-hydroxybutyrate Procurement FAQ

1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.

2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.

3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.

4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.

5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.

6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.

7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.

8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.

9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.

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