2-Trifluoromethyl-5-pyridineboric acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 868662-36-6 |
| Product name | 2-Trifluoromethyl-5-pyridineboric acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Trifluoromethyl-5-pyridineboric acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Trifluoromethyl-5-pyridineboric acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Trifluoromethyl-5-pyridineboric acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Synthesis of fluorinated pharmaceutical intermediates | Used in Suzuki coupling reactions |
| Agrochemical Industry | Preparation of fluorinated agrochemical active ingredients | Applied in organic synthesis reactions |
| Materials Chemistry | Synthesis of fluorinated functional materials | Applied in polymerization or modification reactions involving boronic acids |
| Chemical Research | Laboratory reagent for organic synthesis | Applied in various organic transformation reactions |
Manufacturing Quality Control of 2-Trifluoromethyl-5-pyridineboric acid
| Test Item | Common Testing Method | Method Description |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, physical state (e.g., white to off-white powder), whether it is lumpy or contains visible impurities. |
| Purity (Active Ingredient Content) | High-Performance Liquid Chromatography (HPLC) | Use a reverse-phase C18 column and a UV detector (e.g., at 254 nm). Qualify by retention time and quantify using peak area normalization or external standard method for active ingredient content. |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Confirm the compound structure using ¹H NMR and ¹³C NMR. Characteristic peaks include protons from the pyridine ring, signals from the trifluoromethyl group, and ortho hydrogen signals from the boronic acid group. |
| Fluorine Group Identification | Fluorine Nuclear Magnetic Resonance (¹⁹F NMR) | Detect characteristic chemical shifts of the trifluoromethyl group (–CF₃) typically in the range of -60 to -65 ppm for structural verification. |
| Moisture Content | Karl Fischer Titration | Determine the total amount of bound and free water to ensure that the boric acid derivative does not decompose or decrease in purity due to hygroscopicity. |
| Residual Solvents | Gas Chromatography (GC) | Detect organic solvents possibly remaining from the synthesis process (e.g., toluene, tetrahydrofuran, ethanol), in compliance with ICH Q3C limits. |
| Boric Acid Content | Titrimetric Method (Complexometric or Acid-Base Titration) | After forming a complex with boronic acid and polyol compounds such as mannitol, titrate with a standard base solution to indirectly determine the boric acid content. |
| Impurity Analysis | HPLC-MS (Liquid Chromatography-Mass Spectrometry Coupling) | Separate and identify organic impurities (e.g., de-boronated byproducts, oxidation impurities), improving accuracy and sensitivity in impurity identification. |
| Melting Point | Melting Point Apparatus Measurement | Determine the melting range using a capillary method to assess the compound’s purity and consistency (pure substances usually have sharp melting points). |
| Heavy Metal Residues | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | Detect residual heavy metals such as lead, mercury, cadmium, and palladium from catalysts, ensuring compliance with pharmacopoeia or client-specified limits. |
| Particle Size Distribution (if applicable) | Laser Diffraction Particle Size Analysis | If used as a precursor for formulations, control particle size to ensure solubility and reactivity. |
Technical Specifications of 2-Trifluoromethyl-5-pyridineboric acid
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Trifluoromethyl-5-pyridineboric acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Trifluoromethyl-5-pyridineboric acid
Safety Information of 2-Trifluoromethyl-5-pyridineboric acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-Trifluoromethyl-5-pyridineboric acid
Industrial 2-Trifluoromethyl-5-pyridineboric acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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