(S)-4-(tert-Butoxycarbonyl)morpholine-2-carboxylic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 868689-63-8 |
| Product name | (S)-4-(tert-Butoxycarbonyl)morpholine-2-carboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (S)-4-(tert-Butoxycarbonyl)morpholine-2-carboxylic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (S)-4-(tert-Butoxycarbonyl)morpholine-2-carboxylic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (S)-4-(tert-Butoxycarbonyl)morpholine-2-carboxylic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral intermediate for synthesizing morpholine-containing targeted anticancer drugs (e.g., PI3K/mTOR inhibitors) | Key building block in chiral resolution or asymmetric synthesis routes; incorporated into the active molecular scaffold via deprotection, amidation, and related steps |
| Pharmaceutical R&D | Side-chain modification intermediate for BACE1 inhibitor candidates in Alzheimer’s disease therapy | Chiral morpholine carboxylic acid unit used in solid-phase or solution-phase peptide coupling; coupled with amino components after tert-butyl ester deprotection |
| Fine Chemicals | Starting material for chiral ligands or catalysts | C2-symmetric bis-morpholine ligands prepared via hydroxyl/carboxyl derivatization; applied in asymmetric hydrogenation or epoxidation reactions |
Manufacturing Quality Control of (S)-4-(tert-Butoxycarbonyl)morpholine-2-carboxylic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorption at specific wavelength using reverse-phase chromatography with external standard calibration. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC separation and UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., THF, DMF, EtOAc) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration based on iodine-sulfur dioxide redox reaction. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-OES | Quantifies elemental impurities (e.g., Pb, Cd, Ni, Fe) by plasma excitation and atomic emission spectroscopy. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after anion exchange. |
| Residual tert-Butyl Alcohol | GC-FID | Detects residual t-butanol from esterification step via headspace or direct injection GC analysis. |
| pH of Aqueous Solution | Potentiometric Titration | Measures acidity/basicity of a defined aqueous suspension using calibrated pH electrode. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using controlled heating and visual observation. |
| Loss on Drying | Gravimetric Analysis | Measures volatile content by weight loss after drying under specified temperature and vacuum conditions. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution of solid particles in suspension by measuring angular scattering intensity of laser light. |
Technical Specifications of (S)-4-(tert-Butoxycarbonyl)morpholine-2-carboxylic acid
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (HPLC) |
| Optical Rotation | +38.0 to +46.0° (c=1, in methanol) |
| Melting Point | 128 to 132°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (S)-4-(tert-Butoxycarbonyl)morpholine-2-carboxylic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (S)-4-(tert-Butoxycarbonyl)morpholine-2-carboxylic acid
Safety Information of (S)-4-(tert-Butoxycarbonyl)morpholine-2-carboxylic acid
| Pictograms |   |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (S)-4-(tert-Butoxycarbonyl)morpholine-2-carboxylic acid
Industrial (S)-4-(tert-Butoxycarbonyl)morpholine-2-carboxylic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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