1-BENZHYDRYL-3-FLUORO-AZETIDINE HYDROCHLORIDE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 869488-99-3 |
| Product name | 1-BENZHYDRYL-3-FLUORO-AZETIDINE HYDROCHLORIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-BENZHYDRYL-3-FLUORO-AZETIDINE HYDROCHLORIDE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-BENZHYDRYL-3-FLUORO-AZETIDINE HYDROCHLORIDE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-BENZHYDRYL-3-FLUORO-AZETIDINE HYDROCHLORIDE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Serving as a synthetic intermediate in the development of antitumor agents and central nervous system (CNS) therapeutics | Introducing fluorine via nucleophilic substitution in organic synthesis to construct an azetidine scaffold, followed by coupling with a benzylating reagent and subsequent acidification to yield the hydrochloride salt |
| Pharmaceutical Intermediates | Synthesizing fluorinated azetidine compounds exhibiting favorable bioavailability and metabolic stability | Employing a multi-step synthesis route comprising cyclization, selective fluorination, and hydrochloride salt formation to enhance product purity and stability |
| Biopharmaceuticals | Serving as a lead compound in the design and optimization of targeted protein inhibitors | Leveraging its rigid cyclic structure to strengthen molecular binding to the target, with pharmacological activity evaluated through high-throughput screening |
| Fine Chemicals | Preparing functional molecules with defined chirality or stereoselectivity | Controlling stereochemistry via asymmetric synthesis techniques, using chiral auxiliaries or catalysts for efficient construction |
Manufacturing Quality Control of 1-BENZHYDRYL-3-FLUORO-AZETIDINE HYDROCHLORIDE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210-230 nm, calibrated against certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities by gradient HPLC-UV, relative to main peak using area normalization or external standard method. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify specified organic solvents based on calibrated response factors. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via stoichiometric reaction. |
| Heavy Metals | ICP-MS | Quantification of trace heavy metals (e.g., Pb, Cd, Hg, As) after acid digestion, using isotopic detection and internal standard correction. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using silver indicator electrode to determine chloride ion concentration based on precipitation endpoint. |
| Residue on Ignition | Gravimetric Analysis | Heating sample at 700-800 C to constant weight; residue mass expressed as percentage of original sample. |
| pH of Aqueous Solution | pH Meter Measurement | Direct measurement of pH in a 1% w/v aqueous suspension using calibrated pH meter with glass electrode. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser diffraction to determine D10, D50, D90 values based on Mie scattering theory. |
| Bulk Density | USP <616> Tap Density | Measurement of mass per unit volume before and after standardized tapping; calculated as tapped and bulk density. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and absence testing for specified pathogens using membrane filtration and culture-based enumeration. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light source, reporting observed rotation corrected for concentration and path length. |
Technical Specifications of 1-BENZHYDRYL-3-FLUORO-AZETIDINE HYDROCHLORIDE
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178°C - 182°C |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-BENZHYDRYL-3-FLUORO-AZETIDINE HYDROCHLORIDE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of 1-BENZHYDRYL-3-FLUORO-AZETIDINE HYDROCHLORIDE
Industrial 1-BENZHYDRYL-3-FLUORO-AZETIDINE HYDROCHLORIDE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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