China Factory Direct
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| CAS number | 86984-32-9 |
| Product name | 6-CHLORO-5-NITROQUINOLINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of pharmaceutical intermediates for anti-inflammatory and antimicrobial drug development | Quinoline ring formation via chlorination and nitration, followed by functional group modification |
| Agrochemicals | Agrochemical intermediate for developing novel plant growth regulators or fungicides | Multi-step organic synthesis leveraging the reactivity of the nitro and chloro groups for structural modification |
| Polymers & Advanced Materials | Synthesis of functional polymer monomers to enhance thermal resistance and stability | Introduction of the quinoline backbone via coupling or polymerization reactions to improve material performance |
| Fine Chemicals | Synthesis of dyes, fluorescent materials, and other fine chemicals | Construction of complex aromatic systems starting from 6-chloro-5-nitroquinoline, using reduction, coupling, and related processes |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Related Substances | HPLC-UV or HPLC-DAD | Separation and identification of structurally related impurities (e.g., 5-nitroquinoline, 6-chloroquinoline, des-nitro/des-chloro analogs) using gradient elution and diode-array detection. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common process solvents (e.g., DMF, dichloromethane, toluene) against calibrated standards. |
| Heavy Metals (as Pb) | ICP-MS or AAS | Quantification of toxic elements (Pb, Cd, Hg, As, Cr) after acid digestion; ICP-MS offers multi-element trace-level sensitivity, AAS provides single-element accuracy per USP <232>/<233>. |
| Chloride Content | Potentiometric Titration with AgNO₃ | Direct titration with silver nitrate using a silver indicator electrode; measures inorganic chloride ions released upon alkaline hydrolysis. |
| Moisture Content | Karl Fischer Coulometric Titration | Electrochemical quantification of water content based on stoichiometric iodine generation and reaction with sample water in anhydrous methanol medium. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid phase transition temperature range using calibrated capillary tube method per USP <741>. |
| Particle Size Distribution | Laser Diffraction (Dry Dispersion) | Measurement of size distribution by analyzing angular scattering pattern of laser light passing through dispersed powder aerosol. |
| Organic Volatile Impurities (e.g., Nitrobenzene) | GC-MS | Identification and quantification of genotoxic impurities using gas chromatography coupled with mass spectrometric detection and library matching. |
| Sulfated Ash | Gravimetric Analysis | Residue weight after controlled incineration at 500–600 °C following sulfuric acid treatment, indicating inorganic residue content per USP <281>. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white to light yellow crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 158–162°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.