6-Chloropurine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 87-42-3 |
| Product name | 6-Chloropurine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 6-Chloropurine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 6-Chloropurine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 6-Chloropurine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Intermediate for antimetabolite drugs | Serves as the core scaffold for synthesizing purine-based antineoplastic agents and immunosuppressants, including mercaptopurine, thioguanine, and azathioprine. |
| Pharmaceutical Industry | Intermediate for antiviral drugs | Used as a key starting material to synthesize precursors of antiviral agents—such as acyclovir and ganciclovir—via functional group transformations. |
| Agrochemical Industry | Intermediate for plant growth regulators | Applied in the synthesis of cytokinin-type plant growth regulators, such as 6-benzylaminopurine (6-BA), to promote plant cell division. |
| Biochemical Research | Enzyme inhibitor and probe | Functions as an inhibitor of enzymes including adenosine deaminase in biochemical assays to study purine metabolism pathways. |
| Organic Synthesis | Chemical reagent | Employed as a key nitrogen-containing heterocycle for constructing purine derivative libraries and participating in nucleophilic substitution reactions to introduce additional functional groups. |
Manufacturing Quality Control of 6-Chloropurine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~260 nm, based on peak area comparison against a certified reference standard. |
| Residual Solvents | GC-FID | Separation and quantification of volatile organic solvents (e.g., methanol, acetone, DMF) using capillary GC with flame ionization detection and internal standard calibration. |
| Heavy Metals (as Pb) | ICP-MS | Multi-element trace metal quantification after acid digestion, utilizing inductively coupled plasma mass spectrometry for sub-ppq sensitivity and isotopic specificity. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride anion using suppressed conductivity detection after eluent gradient separation on an anion-exchange column. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration where iodine generated coulometrically reacts stoichiometrically with water; measures trace moisture content in solid samples. |
| Related Substances | HPLC-DAD | Identification and quantification of structurally related impurities (e.g., 6-hydroxypurine, 2,6-dichloropurine) using HPLC with diode-array detection and spectral library matching. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing the temperature range over which the solid phase converts to liquid under controlled heating rate. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Determination of inorganic ash content by incinerating the sample at 700–800 °C and measuring residual mass after cooling. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution in dispersed solid samples via angular scattering pattern of laser light, converted using Mie theory. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral impurities or degradation products in solution at specified wavelength and temperature. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Determination of surface acidity/basicity by measuring hydrogen ion activity in a defined aqueous suspension using a calibrated glass electrode system. |
| Microbial Contamination | Membrane Filtration & Colony Counting | Enumeration of viable aerobic microorganisms after filtration, membrane transfer to culture media, and incubation per pharmacopeial guidelines (e.g., USP <61>). |
Technical Specifications of 6-Chloropurine
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 210-215°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 6-Chloropurine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 6-Chloropurine
Packaging of 6-Chloropurine
Industrial 6-Chloropurine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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