(R)-1-Cbz-3-Aminopyrrolidine hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 870621-17-3 |
| Product name | (R)-1-Cbz-3-Aminopyrrolidine hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (R)-1-Cbz-3-Aminopyrrolidine hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (R)-1-Cbz-3-Aminopyrrolidine hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (R)-1-Cbz-3-Aminopyrrolidine hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of antiviral and antitumor agents | Used as a key intermediate in organic synthesis to construct complex molecular frameworks |
| Biochemistry | Synthesis of amino acid derivatives and peptide compounds | Applied as an amino donor or structural building block in solid-phase or solution-phase peptide synthesis |
| Chemical Synthesis | Chiral auxiliary in the synthesis of chiral compounds and asymmetric synthesis | Introduces chiral centers via stereoselective reactions to enhance product enantiomeric purity |
| Polymer Materials | Monomer for functional polymer synthesis | Employed in the preparation of specialty polymers, such as separation membranes or stimuli-responsive materials |
Manufacturing Quality Control of (R)-1-Cbz-3-Aminopyrrolidine hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210-230 nm, comparing peak area to reference standard. |
| Chiral Purity | Chiral HPLC | Separates (R)- and (S)-enantiomers on a chiral stationary phase; enantiomeric excess calculated from peak areas. |
| Loss on Drying | Gravimetric Analysis | Measures weight loss after drying under controlled temperature and vacuum to determine volatile content. |
| Residual Solvents | GC-FID | Detects and quantifies residual solvents (e.g., MeOH, EtOAc, DMF) using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-OES | Quantifies trace metal impurities (e.g., Pb, Cd, Ni, Fe) by plasma excitation and elemental emission spectroscopy. |
| Chloride Content | Potentiometric Titration | Determines chloride ions via titration with silver nitrate using a silver/silver chloride electrode for endpoint detection. |
| Water Content | Karl Fischer Titration | Measures water by coulometric or volumetric reaction of iodine with water in anhydrous methanol-based medium. |
| Related Substances | HPLC-UV | Identifies and quantifies structurally related impurities (e.g., de-Cbz, diastereomers, hydrolysis products) using gradient HPLC. |
| Optical Rotation | Polarimetry | Measures specific rotation at sodium D-line (589 nm) to confirm chiral identity and batch consistency. |
| pH of Solution | pH Potentiometry | Determines acidity of aqueous suspension (e.g., 1% w/v) using calibrated pH electrode, indicating salt stability and residual acid/base. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder size distribution by measuring angular scattering pattern of laser beam passing through dispersed sample. |
| Microbial Limits | Membrane Filtration | Detects aerobic microorganisms and specified pathogens (e.g., E. coli, S. aureus) via filtration, incubation, and colony enumeration. |
Technical Specifications of (R)-1-Cbz-3-Aminopyrrolidine hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Optical Rotation | -16.0 to -13.0 deg (c=1, in 1M HCl) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Melting Point | 178 to 182 °C |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (R)-1-Cbz-3-Aminopyrrolidine hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (R)-1-Cbz-3-Aminopyrrolidine hydrochloride
Safety Information of (R)-1-Cbz-3-Aminopyrrolidine hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (R)-1-Cbz-3-Aminopyrrolidine hydrochloride
Industrial (R)-1-Cbz-3-Aminopyrrolidine hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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