4-Chloro-3-cyanophenylboronic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 871332-95-5 |
| Product name | 4-Chloro-3-cyanophenylboronic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Chloro-3-cyanophenylboronic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Chloro-3-cyanophenylboronic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Chloro-3-cyanophenylboronic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing active pharmaceutical ingredients (APIs), including antitumor agents and kinase inhibitors | Suzuki-Miyaura coupling to construct aryl–aryl bonds |
| Agrochemicals | Structural building block for synthesizing novel herbicides or insecticides | Palladium-catalyzed cross-coupling to introduce chlorocyanophenyl functionality |
| Materials Science | Precursor for organic optoelectronic materials (e.g., OLED emissive layer materials) | Coupling reactions involving boronic acids to build conjugated molecular frameworks |
Manufacturing Quality Control of 4-Chloro-3-cyanophenylboronic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time matching and threshold limits per ICH Q3A/B. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., THF, methanol, toluene) against calibrated standards. |
| Water Content | Karl Fischer Titration | Electrochemical titration measuring water via iodine-sulfur dioxide reaction in pyridine-free reagent system. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As, Ni) after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppb sensitivity. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residue after microwave-assisted acid digestion using inductively coupled plasma optical emission spectrometry. |
| Chloride Ion Impurity | Ion Chromatography | Separation and conductivity detection of chloride anions using anion-exchange column and suppressed conductivity detection. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by observing solid-to-liquid phase change under controlled heating rate per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under standardized white light and against defined reference standards. |
| Particle Size Distribution | Laser Diffraction | Measurement of size distribution in dry powder form using Mie scattering theory and automated dispersion. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a 1% w/v suspension in purified water using calibrated pH electrode per EP 2.2.3. |
| Loss on Drying | Gravimetric Method | Weight loss determination after drying at 105 C for 2 hours under vacuum, reflecting volatile content including residual solvents and moisture. |
Technical Specifications of 4-Chloro-3-cyanophenylboronic acid
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 145–149°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Chloro-3-cyanophenylboronic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Chloro-3-cyanophenylboronic acid
Safety Information of 4-Chloro-3-cyanophenylboronic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-Chloro-3-cyanophenylboronic acid
Industrial 4-Chloro-3-cyanophenylboronic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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