China Factory Direct
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| CAS number | 872-85-5 |
| Product name | 4-Pyridinecarboxaldehyde |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of histamine H2-receptor antagonists, such as cimetidine and ranitidine | Organic synthetic condensation reaction |
| Pharmaceuticals | Raw material for synthesizing 4-pyridylmethylamine and its derivatives | Reductive amination reaction |
| Chemicals / Research | Used to prepare pyridyl Schiff base ligands | Condensation reaction |
| Chemicals / Research | Applied in the synthesis of pyridine-containing heterocyclic compounds or functional coordination complexes | Catalytic coupling or cyclization reaction |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color and physical state (typically a colorless to pale yellow liquid or crystalline solid), checking for clarity and presence of impurities. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with methanol/water or acetonitrile/water as mobile phase, and a UV detector (e.g., 254 nm) to measure the main peak area for purity calculation. |
| Assay | HPLC or Gas Chromatography (GC) | HPLC is suitable for thermally unstable samples; GC is used for volatile and thermally stable compounds, with quantification via internal or external standard methods. |
| Melting Point | Melting Point Apparatus | Determine the melting temperature range of the solid sample and compare it with the reference value (approximately 62–65 °C) to assess purity and crystal form consistency. |
| Water Content | Karl Fischer Titration | Use volumetric or coulometric method to determine water content in the sample, controlling the impact of moisture on stability and subsequent reactions. |
| Residual Solvents | Gas Chromatography (GC) | Analyze residual organic solvents (e.g., toluene, ethanol, dichloromethane) from synthesis or purification processes using headspace or direct injection. |
| pH (Solution) | pH Meter | Prepare an aqueous solution of defined concentration and measure pH using a calibrated pH meter to evaluate the influence of acidic or basic impurities. |
| UV-Visible Absorption Spectroscopy | UV-Visible Spectrophotometry (UV-Vis) | Scan absorption peaks within a specific wavelength range (e.g., 250–300 nm) for qualitative identification and supplementary purity assessment. |
| Structural Confirmation | Proton Nuclear Magnetic Resonance (¹H NMR) Fourier Transform Infrared Spectroscopy (FT-IR) Mass Spectrometry (MS) |
¹H NMR confirms aldehyde proton (~9.9 ppm) and pyridine ring proton signals; FT-IR identifies characteristic peaks such as C=O (~1690 cm⁻¹) and C=N; MS verifies the molecular ion peak (m/z = 107 [M]⁺). |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) |
Detect residual toxic metal elements such as lead, cadmium, mercury, and arsenic to ensure compliance with pharmacopoeial or chemical safety standards. |
| Related Substances (Impurities) | HPLC or GC | Use gradient elution (HPLC) or programmed temperature (GC) to separate and quantify process impurities and degradation products (e.g., 4-pyridylcarboxylic acid, dimers, etc.). |
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
| Odor | Characteristic pungent odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.