TETRAHYDRO-2H-PYRAN-3-CARBOXYLIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 873397-34-3 |
| Product name | TETRAHYDRO-2H-PYRAN-3-CARBOXYLIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for TETRAHYDRO-2H-PYRAN-3-CARBOXYLIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk TETRAHYDRO-2H-PYRAN-3-CARBOXYLIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of TETRAHYDRO-2H-PYRAN-3-CARBOXYLIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in the synthesis of antiviral agents, protease inhibitors, and other active pharmaceutical ingredients (APIs) | Serves as a chiral building block in multistep organic synthesis, commonly incorporated via esterification, reduction, coupling, and related reactions to construct complex molecular frameworks |
| Pesticide Development | Functions as a structural modification unit for novel insecticides or fungicides | Introduces heterocyclic carboxylic acid groups to optimize compound lipophilicity and target-binding affinity |
| Materials Science | Acts as a functional monomer for synthesizing specialty polymers or liquid crystal materials | Introduces tetrahydropyran ring structures via condensation or ring-opening polymerization to enhance material thermal stability and solubility |
Manufacturing Quality Control of TETRAHYDRO-2H-PYRAN-3-CARBOXYLIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, THF, ethyl acetate) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific rotation using sodium D-line light source in solution; verifies chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-MS | Quantitative multi-element analysis after acid digestion; detects metals (e.g., Pb, Cd, Ni, Fe) at sub-ppb levels per ICH Q3D. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride anion using suppressed conductivity detection with standard calibration. |
| Residue on Ignition | Gravimetric Analysis | Ignition at 700-800 C followed by weighing of non-volatile inorganic residue to assess inorganic impurity load. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using controlled heating rate; confirms identity and crystallinity per pharmacopeial monographs. |
| pH (1% w/v aqueous solution) | pH Meter | Potentiometric measurement using calibrated pH electrode in aqueous suspension; indicates acidic character and potential hydrolysis. |
| Appearance | Visual Inspection | Assessment of color and clarity against water-white standard under controlled lighting; detects particulates or discoloration. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser scattering principle to determine D10, D50, D90 values for process consistency. |
Technical Specifications of TETRAHYDRO-2H-PYRAN-3-CARBOXYLIC ACID
| Test Item | Specification |
|---|---|
| Appearance | Colorless to light yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | -25 to -20°C |
| Optical Rotation | +15.0 to +19.0° (c=1, in methanol) |
| Acid Value (mg KOH/g) | 145 to 155 mg KOH/g |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of TETRAHYDRO-2H-PYRAN-3-CARBOXYLIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of TETRAHYDRO-2H-PYRAN-3-CARBOXYLIC ACID
Safety Information of TETRAHYDRO-2H-PYRAN-3-CARBOXYLIC ACID
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of TETRAHYDRO-2H-PYRAN-3-CARBOXYLIC ACID
Industrial TETRAHYDRO-2H-PYRAN-3-CARBOXYLIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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