4-(Chloromethyl)tolunitrile Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 874-86-2 |
| Product name | 4-(Chloromethyl)tolunitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-(Chloromethyl)tolunitrile
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-(Chloromethyl)tolunitrile Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-(Chloromethyl)tolunitrile
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Key intermediate in the production of benzodiazepine active pharmaceutical ingredients (e.g., bromazepam) | Condensation and cyclization with amine derivatives to construct the 1,4-benzodiazepine core scaffold |
| Pharmaceutical Industry | Intermediate in the synthesis of the antidepressant milnacipran | Serves as a cyanide source in nucleophilic substitution to introduce the cyanide side chain |
| Pharmaceutical Industry | Intermediate in the preparation of antiallergic and antihistaminic agents | Alkylation leveraging the reactivity of the benzyl chloride group |
| Agrochemical Industry | Intermediate in the synthesis of benzoylurea insecticides (e.g., chlorfluazuron, flufenoxuron) | Hydrolysis followed by acid chloride formation to yield p-chlorobenzoyl chloride, or direct incorporation into the benzoylurea structure |
| Agrochemical Industry | Intermediate in the preparation of pyrethroid insecticides (e.g., fenvalerate) | Hydrolysis and acidification to produce p-chlorophenylacetic acid, subsequently used in the synthesis of pyrethroid esters |
| Agrochemical Industry | Intermediate in the production of diphenyl ether herbicides (e.g., oxyfluorfen) | Hydrolysis to generate p-chlorophenylacetic acid or its derivatives, followed by synthesis of diphenyl ether compounds |
| Dyes & Pigments Industry | Intermediate in the synthesis of fluorescent whitening agents and organic pigments | Leverages dual reactivity of the cyano and chloromethyl groups to introduce heterocyclic structures or extend conjugation |
| Fragrance Industry | Intermediate in fragrance synthesis | Grignard reaction or hydrolytic reduction to prepare phenylethanol derivatives exhibiting floral or fruity odors |
| Polymer Materials Industry | Precursor for functional monomers and resin modifiers | Reaction with polymer chains bearing active hydrogen to incorporate polar cyano groups and enhance resin performance |
Manufacturing Quality Control of 4-(Chloromethyl)tolunitrile
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity (Main Component Content) | Gas Chromatography (GC) | Using capillary columns (e.g., DB-5 or HP-5) and FID detector, with internal or external standard quantification methods. It can effectively separate para-cyanobenzyl chloride and its organic impurities (such as ortho-isomers, unreacted raw materials), offering high resolution and good reproducibility. |
| Moisture Content | Karl Fischer Titration | Based on the quantitative reaction between iodine and sulfur dioxide in pyridine and methanol with water, using potentiometric or coulometric methods to determine trace moisture content in the sample (typically required ≤0.1%). |
| Chloride Content (Inorganic Chloride) | Ion Chromatography (IC) or Oxygen Bomb Combustion + Ion-Selective Electrode | The sample is combusted in an oxygen bomb and absorbed into an alkaline solution, converting to chloride ions, which are then determined by ion chromatography; alternatively, a chloride ion-selective electrode can be used to directly measure Cl⁻ concentration in hydrolyzed solution, for controlling inorganic chloride impurities (such as residual HCl). |
| Heavy Metal Content | Atomic Absorption Spectrometry (AAS) or ICP-MS | After acid digestion of the sample, AAS is used to determine heavy metals such as lead, cadmium, and mercury; or ICP-MS can be used for simultaneous multi-element detection, meeting pharmacopoeia or ICH Q3D limits (usually ≤10 ppm). |
| Volatile Organic Impurities | Gas Chromatography-Mass Spectrometry (GC-MS) | Volatile impurities are separated by GC and identified by MS, used to detect residual solvents or degradation products such as benzene, toluene, chlorobenzene, and hydrogen cyanide, meeting ICH Q3C standards. |
| Appearance and Color | Visual Colorimetric Method or Colorimeter Measurement | According to the Chinese Pharmacopoeia or ASTM E308 standards, the color of liquid or molten samples is visually assessed or measured using a colorimeter in terms of platinum-cobalt (Pt-Co) or APHA color units, ensuring no obvious colored impurities. |
| Melting Point | Melting Point Apparatus | A digital melting point apparatus is used to determine the melting range of the pure compound (literature value about 29–31°C), used for preliminary identification and purity evaluation. Impurities may cause a lower melting point or a broader melting range. |
| pH Value (in Aqueous Solution) | pH Meter Measurement | A small amount of the sample is dissolved in water (or ethanol-water mixture), and the acidity or alkalinity is measured using a calibrated pH meter. Para-cyanobenzyl chloride hydrolyzes to show weak acidity; abnormal pH values may indicate hydrolysis or acidic impurity residues. |
| Cyano Group Content (Qualitative/Quantitative) | Fourier Transform Infrared Spectroscopy (FT-IR) or UV-Visible Spectroscopy | The characteristic absorption peak at approximately 2240 cm⁻¹ (—C≡N stretching vibration) in FT-IR is used for qualitative confirmation; UV-Vis has absorption peaks at 270–280 nm, which can be used for quantitative analysis with a calibration curve. |
Technical Specifications of 4-(Chloromethyl)tolunitrile
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 64–67°C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Identification (IR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-(Chloromethyl)tolunitrile
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-(Chloromethyl)tolunitrile
Packaging of 4-(Chloromethyl)tolunitrile
Industrial 4-(Chloromethyl)tolunitrile Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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