China Factory Direct
|
|
| CAS number | 875-35-4 |
| Product name | 2,6-Dichloro-4-methylnicotinonitrile |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for synthesizing agrochemicals such as herbicides and insecticides | Further functionalized via nucleophilic substitution, reduction, or coupling reactions to construct the active molecular scaffold |
| Pharmaceuticals | Synthesis of biologically active drug molecules (e.g., anticancer and antiviral candidates) | Used as a pyridine-based heterocyclic building block in multistep organic synthesis—for example, conversion of the cyano group to amide or carboxylic acid functionalities |
| Fine Chemicals | Preparation of other nitrogen-containing heterocyclic functional materials or ligands | Functionalized via cyanide hydrolysis, reduction, or reaction with metal reagents to introduce required functional groups |
| Test Item | Common Test Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, state, and presence of visible impurities under natural light or standard light sources. Typically appears as white to off-white crystalline powder. |
| Identification | Infrared Spectroscopy (IR) High-Performance Liquid Chromatography (HPLC) Proton Nuclear Magnetic Resonance Spectroscopy (¹H NMR) |
- IR: Identify by comparing the infrared absorption spectrum features with those of the reference standard. - HPLC: Compare the retention time of the sample with that of the reference substance under specific chromatographic conditions. - ¹H NMR: Analyze the chemical shift of hydrogen atoms in the sample to match the standard structure and confirm the molecular structure. |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reverse-phase C18 column with methanol-water or acetonitrile-water as the mobile phase, detect using a UV detector (e.g., 254 nm), and calculate the main component content using external or internal standard methods. Typically requires ≥98.0%. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Use gradient elution to separate the main component from potential impurities (such as synthetic intermediates, by-products, degradation products). Control the limits of each impurity using area normalization or correction factor methods (e.g., single impurity ≤0.5%, total impurities ≤1.0%). |
| Moisture | Karl Fischer Titration | Determine moisture content using either the volumetric or coulometric method. Control moisture content to be generally ≤0.5%. |
| Residual Solvents | Gas Chromatography (GC) | Follow ICH Q3C guidelines, use headspace or direct injection GC-FID/MS to detect residual organic solvents (e.g., toluene, dichloromethane, ethanol), and ensure compliance with the specified limits. |
| Melting Point | Capillary Melting Point Method | Pack the sample into a capillary tube and slowly heat it in a melting point apparatus, recording the temperature range from initial melting to complete melting. Compare with literature values (approximately 120–124°C). |
| Residue on Ignition / Ash Content | High-Temperature Incineration Method | Heat the sample at high temperatures (e.g., 600–800°C) and weigh the remaining inorganic residue. Typically control the limit to ≤0.1%. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) |
Dissolve the sample and determine the total content of heavy metals such as lead, cadmium, mercury, and arsenic, ensuring compliance with pharmacopoeial or regulatory limits (e.g., ≤20 ppm). |
| Test Item | Specification |
|---|---|
| Appearance | White powder |
| Assay | Min. 99% |
| M.P. | 108-111°C |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.