5-Bromo-2-fluoropyridine-3-carboxaldehyde Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 875781-15-0 |
| Product name | 5-Bromo-2-fluoropyridine-3-carboxaldehyde |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-Bromo-2-fluoropyridine-3-carboxaldehyde
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-Bromo-2-fluoropyridine-3-carboxaldehyde Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-Bromo-2-fluoropyridine-3-carboxaldehyde
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Intermediate for anticancer drugs | Serves as a key building block in Suzuki coupling or nucleophilic substitution reactions to construct lead compounds containing pyridine moieties. |
| Pharmaceutical Chemicals | Synthesis of tyrosine kinase inhibitors | Enables selective functionalization via bromine and fluorine atoms on the pyridine ring to synthesize inhibitors targeting specific receptors (e.g., EGFR, VEGFR). |
| Agrochemicals | Development of pesticide active ingredients | Used as a precursor for structural modification in synthesizing novel pyridine-containing insecticides or fungicides. |
| Organic Synthesis | Organic synthesis building block | Converted into pyridin-3-ylmethanol or pyridine-3-carboxylic acid derivatives with varied substitution patterns via reduction, oxidation, or condensation reactions. |
| Research Reagents | Synthesis of functional materials | Employed in preparing organic luminescent materials or ligands by introducing specific functional groups or conjugated systems via the aldehyde group. |
Manufacturing Quality Control of 5-Bromo-2-fluoropyridine-3-carboxaldehyde
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., starting materials, intermediates, dehalogenated by-products) using gradient HPLC-UV. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., DMF, THF, methanol) by gas chromatography with flame ionization detection using headspace sampling. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine generated electrochemically in pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Quantifies toxic elements (Pb, Cd, Hg, As, Ni) at sub-ppb levels using inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue by ignition at 700-800 C and weighing the ash. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white light against standard reference. |
| Bulk Density | USP <616> Tap Density Tester | Measures mass per unit volume after standardized tapping; evaluates powder flow and handling characteristics. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution by analyzing angular scattering pattern of laser beam passed through dispersed sample. |
| Optical Rotation | Polarimetry | Measures specific rotation using sodium D-line light to confirm chiral purity (if applicable) or detect racemization. |
Technical Specifications of 5-Bromo-2-fluoropyridine-3-carboxaldehyde
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-Bromo-2-fluoropyridine-3-carboxaldehyde
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-Bromo-2-fluoropyridine-3-carboxaldehyde
Safety Information of 5-Bromo-2-fluoropyridine-3-carboxaldehyde
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 5-Bromo-2-fluoropyridine-3-carboxaldehyde
Industrial 5-Bromo-2-fluoropyridine-3-carboxaldehyde Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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