China Factory Direct
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| CAS number | 875781-17-2 |
| Product name | 5-BROMO-1H-PYRAZO[3,4-B]PYRIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process Description |
|---|---|---|
| Pharmaceutical R&D | Pharmaceutical Intermediates | Used as a key intermediate in the synthesis of anticancer, antiviral, and kinase inhibitor drugs; employed in constructing heterocyclic compounds |
| Agrochemical R&D | Agrochemical Intermediates | Applied in synthesizing biologically active agrochemical compounds to enhance compound stability and bioactivity |
| Fine Chemicals | Organic Synthesis Reagents | Serves as a critical precursor in cross-coupling reactions such as Suzuki and Heck couplings for constructing complex pyridine frameworks |
| Materials Science | Functional Material Synthesis | Used as a synthetic intermediate for optoelectronic materials and organic semiconductor materials |
| Biotechnology | Molecular Probe Synthesis | Applied in synthesizing molecular probes for biological labeling and detection in bioactivity studies |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at characteristic wavelength, calibrated against certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities by gradient HPLC-UV, comparing retention times and peak areas to reference standards or threshold limits. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents using gas chromatography with flame ionization detection, per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content based on stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Multi-element detection and quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after anion exchange separation. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after high-temperature ashing at 700-800 C, expressed as percentage weight loss. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity of sample against defined specifications under controlled lighting conditions. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light by chiral compound in solution, indicating enantiomeric purity and identity. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution in dry or dispersed state using Mie scattering theory and laser diffraction instrumentation. |
| Bulk and Tapped Density | Tap Density Analyzer | Determination of bulk density and tapped density using standardized mechanical tapping procedure per USP <616>. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Conforms to reference standard |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.