China Factory Direct
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| CAS number | 876-72-2 |
| Product name | 4-Chloroindole-3-carbaldehyde |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceutical R&D | Key raw material for synthesizing indole alkaloids and pharmaceutical intermediates | Used in condensation, reduction, or cyclization reactions to construct complex molecular frameworks for antitumor, anti-inflammatory, or neuroactive compounds |
| Agrochemical R&D | Used to synthesize bioactive indole derivative agrochemical lead compounds | Participates in heterocycle construction reactions—such as Vilsmeier–Haack formylation followed by derivatization—to generate potential insecticidal or fungicidal structures |
| Organic Synthesis | Multifunctional building block for introducing the chloroindolecarbaldehyde structural motif | The aldehyde group undergoes transformations including Wittig olefination, Knoevenagel condensation, or reductive amination; the chlorine atom participates in nucleophilic substitution or metal-catalyzed cross-coupling reactions |
| Materials Science | Explored for potential applications in optoelectronic materials or coordination polymers (research stage) | The aldehyde group condenses with nitrogen- or oxygen-containing ligands to form Schiff base structures, or serves as a ligand precursor in metal–organic framework (MOF) synthesis |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., unreacted indole, chlorination by-products) using gradient HPLC-UV with system suitability criteria. |
| Residual Solvents | GC-FID | Identifies and quantifies volatile organic solvents (e.g., DMF, dichloromethane) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine generation in pyridine-methanol medium. |
| Heavy Metals | ICP-OES | Measures total heavy metal content (Pb, Cd, Hg, Ni, Cr) after acid digestion by inductively coupled plasma optical emission spectrometry. |
| Chloride Ion Impurity | Ion Chromatography | Quantifies inorganic chloride using suppressed conductivity detection after anion exchange separation. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| Loss on Drying | Gravimetric Method | Measures volatile matter loss by weighing sample before and after drying at 105 C for 2 hours under vacuum. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of visible particulates or discoloration against white/black background under controlled lighting. |
| Acid Value | Acid-Base Titration | Determines free acidic impurities by titration with standardized NaOH solution using phenolphthalein indicator. |
| Residue on Ignition | Sulfated Ash Method | Measures non-volatile inorganic residue after ignition at 600 C following sulfuric acid treatment. |
| Particle Size Distribution | Laser Diffraction | Measures size distribution of solid particles in suspension using Mie scattering theory and calibrated laser diffraction instrument. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 128–132°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.