3-(1-Piperazinyl)-1,2-benzisothiazole Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 87691-87-0 |
| Product name | 3-(1-Piperazinyl)-1,2-benzisothiazole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-(1-Piperazinyl)-1,2-benzisothiazole
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-(1-Piperazinyl)-1,2-benzisothiazole Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-(1-Piperazinyl)-1,2-benzisothiazole
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthetic intermediate for active pharmaceutical ingredients (e.g., paliperidone and other antipsychotics) | Chemical synthesis |
| Chemicals | Organic synthesis building block for compounds containing piperazine and benzisothiazole moieties | Condensation and substitution reactions |
Manufacturing Quality Control of 3-(1-Piperazinyl)-1,2-benzisothiazole
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Identification Test | Infrared Spectroscopy (IR) | By measuring the infrared absorption spectrum of the sample and comparing it with the standard reference spectrum, this method confirms the presence of characteristic functional groups in the molecule (e.g., benzisothiazole ring, piperazine ring). |
| High-Performance Liquid Chromatography (HPLC) Retention Time Comparison | Under specified chromatographic conditions, the retention time of the main peak of the sample should match that of the reference standard, used for preliminary identification. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Using a reversed-phase C18 column, with a mobile phase composed of an appropriate ratio of buffer salt and organic solvent (e.g., acetonitrile/phosphate buffer), detected by UV detector (typically around 254 nm). The content of the main component is calculated using the external standard method. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Employing gradient or isocratic elution programs to separate the main component from potential impurities (e.g., synthetic intermediates, degradation products). Impurity levels are controlled using area normalization or the principal component self-control method with correction factors. |
| Residual Solvents | Gas Chromatography (GC) | According to ICH Q3C guidelines, using headspace injection or direct injection with FID detection, to determine potentially residual organic solvents such as dichloromethane, methanol, ethanol, and N,N-dimethylformamide. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Constant-Pressure Drying Method | Drying the sample at a specified temperature (e.g., 105°C) until constant weight, to measure the percentage of mass loss due to moisture or other volatile components. |
| Residue on Ignition | High-Temperature Incineration Method | Charring and ashing the sample at high temperature (typically 700–800°C), to determine the amount of inorganic impurities, used to control the presence of inorganic salts or metal catalyst residues. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | After sample preparation according to general pharmacopoeia procedures, the concentrations of heavy metals such as lead, cadmium, mercury, and arsenic are determined to ensure compliance with safety limits. |
| pH Value (if formulated into solution) | pH Meter Measurement | Preparing a solution of the sample at a defined concentration, then measuring its acidity or alkalinity using a calibrated pH meter, to assess stability and suitability. |
Technical Specifications of 3-(1-Piperazinyl)-1,2-benzisothiazole
| Test Item | Specification |
|---|---|
| Appearance | White to light yellow crystalline powder |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-(1-Piperazinyl)-1,2-benzisothiazole
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-(1-Piperazinyl)-1,2-benzisothiazole
Safety Information of 3-(1-Piperazinyl)-1,2-benzisothiazole
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 3-(1-Piperazinyl)-1,2-benzisothiazole
Industrial 3-(1-Piperazinyl)-1,2-benzisothiazole Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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