(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 877399-00-3 |
| Product name | (R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 877399-00-3
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 877399-00-3 Supplier from China
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Industrial Applications of 877399-00-3
| Industry | Application | Process |
|---|---|---|
| Pesticides | Insecticides | Used as an active ingredient in the synthesis of pesticide formulations for targeted pest control |
| Pharmaceuticals | Intermediate | Applied as a key intermediate in the synthesis of certain drug molecules, particularly in anticancer drug research and development |
| Biological Research | Bioactivity Testing | Applied in laboratory bioactivity testing on cells or organisms to evaluate potential biological effects |
| Chemical Synthesis | Synthesis of Other Compounds | Used as a starting material or intermediate in the synthesis of other complex organic compounds |
Manufacturing Quality Control of 877399-00-3
| Test Item | Common Testing Method | Method Description |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) | Confirm compound structure by characteristic functional group absorption peaks (e.g., N–H, C–Br, C–F, aromatic rings, etc.). |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Analyze hydrogen atom chemical shifts, coupling constants, and integral ratios to verify molecular structure and stereochemistry (R configuration). | |
| Mass Spectrometry (MS) | Determine molecular ion peaks (M+H⁺ or M+Na⁺, etc.), confirm molecular weight and major fragments, assist in structural identification. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reverse-phase C18 chromatographic column and a UV detector (e.g., 254 nm), employ external standard method or area normalization method to determine the main component content. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Use the same conditions as for content determination or gradient elution programs to separate and quantify process impurities, degradation products, and enantiomers. |
| Enantiomeric Purity | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Separate (R)- and (S)-enantiomers using a chiral stationary phase column; evaluate optical purity (typically requires ee ≥98%). |
| Residual Solvents | Gas Chromatography (GC) | Headspace injection or direct injection, FID detector, detect residual solvents such as methanol and dichloromethane according to ICH Q3C guidelines. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Drying Method | Dry at specified temperature (e.g., 105°C) until constant weight is achieved, measure loss of water and volatile substances. |
| Melting Point | Melting Point Apparatus | Determine the melting temperature range of the sample, serving as a physical constant for identification and preliminary purity assessment. |
| Optical Rotation | Polarimeter | Prepare a solution of specific concentration and measure optical rotation at a specified wavelength (usually sodium D line, 589 nm) to verify chiral purity. |
| Heavy Metals | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | Detect elemental impurities such as lead, cadmium, mercury, and arsenic, meeting ICH Q3D elemental impurity limits. |
| Moisture | Karl Fischer Titration | Specifically determine the moisture content of the sample, particularly suitable for organic compounds sensitive to water. |
Technical Specifications of 877399-00-3
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142–146°C |
| Optical Rotation | -70.0 to -64.0° (c=1, in methanol) |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 877399-00-3
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 877399-00-3
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Industrial 877399-00-3 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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