China Factory Direct
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| CAS number | 88149-49-9 |
| Product name | 2,6-Dibromo-4-(trifluoromethoxy)aniline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of anticancer agents, antiviral agents, or kinase inhibitors | Constructs complex molecular frameworks via nucleophilic substitution and coupling reactions (e.g., Suzuki, Buchwald–Hartwig) |
| Agrochemicals | Used to synthesize biologically active fluorinated aromatic compounds, such as herbicide or fungicide intermediates | Introduces functional groups via halogen exchange, amination, or arylation |
| Materials Science | Building block for liquid crystal monomers or organic optoelectronic materials | Links to conjugated systems via palladium-catalyzed cross-coupling to modulate electronic properties |
| Fine Chemicals | Synthetic precursor to high-value fluorinated aromatic amines | Enables selective functional group transformations leveraging reactivity of the bromo and amino groups |
| Test Item | Common Testing Methods | Method Overview |
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| Appearance | Visual Inspection | Observe the sample's color, physical state (e.g., white to off-white crystalline powder), and presence of foreign particles by naked eye to preliminarily determine whether its physical appearance complies with quality standards. |
| Identification | Infrared Spectroscopy (IR) High-Performance Liquid Chromatography (HPLC) Proton Nuclear Magnetic Resonance (¹H NMR) |
- IR: Measure the sample's infrared absorption spectrum and compare characteristic functional group absorption peaks (e.g., N–H, C–Br, C–F) with a reference spectrum; - HPLC: Under specific chromatographic conditions, compare the retention time of the sample with that of a reference standard; - ¹H NMR: Confirm characteristic signals of aromatic and amino hydrogens in the molecular structure based on chemical shifts and coupling constants. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a mobile phase of methanol-water or acetonitrile-water, detect with a UV detector (typically at ~254 nm), and calculate the main component content using external standard or area normalization methods to ensure purity meets requirements (typically ≥98.0%). |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Under the same or optimized chromatographic conditions as the assay, separate and detect potential process-related impurities (e.g., unreacted starting materials, intermediates) and degradation products. Control individual and total impurity limits using area normalization or main component self-reference methods with correction factors. |
| Water Content | Karl Fischer Titration | Utilize the quantitative reaction between Karl Fischer reagent and water in the sample, and determine water content via potentiometric titration or coulometric methods to control drying level (typically required ≤0.5%). |
| Melting Point | Capillary Melting Point Determination | Load the sample into a melting point capillary tube, slowly heat in a melting point apparatus, and record the temperature range from initial to complete melting. Compare with literature values (e.g., approximately 130–135 °C) to assess purity and crystal form consistency. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace or direct injection with a DB-624 or similar polar capillary column and FID detector to measure residual organic solvents potentially present from manufacturing (e.g., toluene, dichloromethane, ethanol), and control limits according to ICH Q3C guidelines. |
| Residue on Ignition / Ash Content | Gravimetric Method | Ignite the sample at high temperature (typically 700–800 °C) and weigh the mass of residual inorganic matter to evaluate the level of inorganic impurities (typically required ≤0.1%). |
| Test Item | Specification |
|---|---|
| Appearance | Brown solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 118-122°C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.