China Factory Direct
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| CAS number | 881674-06-2 |
| Product name | 1H-Pyrrole-3-carboxylic acid, 5-(2-fluorophenyl)-, ethyl ester |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used in the synthesis of anticancer drug candidates, such as BRAF kinase inhibitor analogs | Under inert atmosphere, undergoes Suzuki coupling with aryl halides, followed by hydrolysis, deprotection, and cyclization to construct the core structure of the target molecule |
| Pesticide R&D | Serves as the pyrrole ring moiety in novel insecticidal molecules to optimize target activity and metabolic stability | Introduces hydrophobic substituents via multistep functional group transformations (e.g., bromination, metallation, cross-coupling), then condenses with heterocyclic amines to form the active precursor |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main compound using reverse-phase HPLC with UV detection at characteristic wavelength, comparing peak area to calibrated standard. |
| Related Substances | HPLC-DAD | Detects and quantifies impurities by retention time and UV spectral matching against reference standards or threshold-based reporting. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents using gas chromatography with flame ionization detection and internal standard calibration. |
| Water Content | Karl Fischer Titration | Determines water via coulometric or volumetric titration using iodine-based reagent where water reacts stoichiometrically with iodine and sulfur dioxide. |
| Heavy Metals | ICP-MS | Measures trace metal contaminants (e.g., Pb, Cd, Ni) by plasma ionization followed by mass spectrometric detection with isotopic resolution. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after controlled combustion with sulfuric acid treatment and high-temperature ignition to constant weight. |
| Optical Rotation | Polarimetry | Determines specific rotation using plane-polarized light passing through a solution to assess chiral purity and identity. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid, indicating crystallinity and presence of impurities. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution of solid particles in suspension by measuring angular variation in laser light scattering intensity. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Determines hydrogen ion activity in saturated aqueous suspension using calibrated glass electrode and reference electrode. |
| Residual Palladium | ICP-OES | Quantifies palladium catalyst residues by plasma excitation and optical emission at element-specific wavelengths with matrix-matched calibration. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 142–146°C |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.